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呼和浩特地区1094例急性脑梗死患者血清维生素B_12、叶酸及同型半胱氨酸的测定分析
引用本文:张保平,刘珊,董莉. 呼和浩特地区1094例急性脑梗死患者血清维生素B_12、叶酸及同型半胱氨酸的测定分析[J]. 国际检验医学杂志, 2013, 34(23): 3172-3173
作者姓名:张保平  刘珊  董莉
作者单位:张保平(内蒙古医科大学附属医院检验科,内蒙古呼和浩特,010050);刘珊(内蒙古医科大学附属医院检验科,内蒙古呼和浩特,010050);董莉(内蒙古医科大学附属医院检验科,内蒙古呼和浩特,010050);
摘    要:目的探讨呼和浩特地区急性脑梗死(ACI)与血清维生素B12、叶酸及同型半胱氨酸(Hcy)的关系。方法将1 094例ACI患者作为ACI组,100例健康体检者作为对照组。采用化学发光法测定其血清维生素B12、叶酸及Hcy浓度。结果 ACI组患者血清叶酸、维生素B12浓度显著低于对照组(P〈0.05)。ACI组患者服用叶酸、维生素B12前、后的血清Hcy浓度均显著高于对照组(P〈0.05)。结论血清维生素B12、叶酸及Hcy检测对ACI的治疗、预后判断具有重要意义。

关 键 词:叶酸  维生素B12  同型半胱氨酸  脑梗死

Analysis of serum vitamin B_12,folic acid and homocysteine detection of 1 094 patients with acute cerebral infarction in Hohhot region
Zhang Baoping,Liu Shan,Dong Li. Analysis of serum vitamin B_12,folic acid and homocysteine detection of 1 094 patients with acute cerebral infarction in Hohhot region[J]. International Journal of Laboratory Medicine, 2013, 34(23): 3172-3173
Authors:Zhang Baoping  Liu Shan  Dong Li
Affiliation:(Department of Clinical Laboratory ,Affiliated Hospital of Inner Mongolia Medical University, Hohhot , Inner Mongolia 010050, China)
Abstract:Objective To explore the relationship of acute cerebral infarction(ACI) with serum vitamin B12,folic acid and homo- cysteine(Hcy).Methods 1 094 patients with ACI served as ACI group and 100 healthy people as control group.Chemilumines- cence was used to detect their serum vitamin B12,folic acid and Hcy concentrations.Results Serum folic acid and vitamin B12 con- centrations of patients in ACI group were significantly lower than those in control group(P〈0.05).Serum Hcy concentration of patients in ACI group before and after taking folic acid and Hcy were significantly higher than that in control group(P〈0.05). Conclusion Serum vitamin B12,folic acid and Hcy detection has important value in ACI treatment and prognosis.
Keywords:folic acid  vitamin B_12  homocysteine  brain infarction
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