网织血小板检测对特发性血小板减少性紫癜的诊断价值

目的探讨网织血小板对特发性血小板减少性紫癜（ITP）的诊断价值。方法选择35例ITP患者作为ITP组,60例健康者作为对照组。治疗前将ITP组患者按血小板计数（PLT）分为2组,PLT〉30×109/L组（n=20）及PLT〈30×109/L组（n=15）。以泼尼松或地塞米松治疗,总疗程为6个月。治疗后根据患者病情是否缓解,分为缓解组及未缓解组。采用Sysmex XE-5000全自动血细胞分析仪检测网织血小板百分比及其绝对值。结果 PLT〉30×109/L组及PLT〈30×109/L组患者的网织血小板百分比明显高于对照组（P〈0.01）,而这两组患者的网织血小板绝对值低于对照组（P〈0.05）。缓解组患者网织血小板百分比及其绝对值与对照组的差异无统计学意义（P〉0.05）,未缓解组患者网织血小板百分比显著高于对照组（P〈0.01）。结论网织血小板的检测对于ITP的诊断、疗效判定具有重要意义。

Clinical value of reticulated platelets counts in idiopathic thrombocytopenic purpura diagnosis

Objective To explore the clinical value of reticulated platelets counts in idiopathic thrombocytopenic purpura（ITP） diagnosis.Methods 35 patients with ITP were served as ITP group and 60 healthy pepeole as control group.Before prednisone or dexamethasone treatment,patients in ITP group were divided into two groups,PLT30×109/L group（n=20） and PLT30× 109/L group（n=15）,according to platelet count（PLT）.After 6 months of total duration treatment,patients in ITP group were di- vided into remission group and non-remission group,according to whether they were in remission.Sysmex XE-5000automated he- matology analyzer was used to detect percentages and absolute values of reticulated platelets.Results The percentages of reticula- ted platelets of patients in PLT30×109/L group and PLT30×109/L group were significantly higher than those in control group（P〈0.01）.The absolute values of reticulated platelets of patients in the both groups were markedly lower than those in con- trol group（P〈0.01）.Percentages and absolute values of reticulated platelets in remission group showed no statistical difference with those in control group（P〈0.05）,while percentages of reticulated platelets in non-remission group were obviously higher than those in control group（P〈0.01）.Conclusion Reticulated platelets count is important for diagnosis and efficacy evaluation of ITP.