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潜、慢型克山病患者柯萨奇B组病毒特异性IgM、 IgG的检测
引用本文:黄汉菊,刘建军,黄振武.潜、慢型克山病患者柯萨奇B组病毒特异性IgM、 IgG的检测[J].华中医学杂志,2001,25(1):5-6.
作者姓名:黄汉菊  刘建军  黄振武
作者单位:1. 华中科技大学同济医学院微生物学教研室
2. 中国预防医学科学院营养与食品卫生研究所
基金项目:卫生部科学研究基金资助项目(No.98-1-066)
摘    要:目的 了解柯萨奇B组病毒(CoxB)感染与克山病的相关关系。方法 采用间接酶联免疫吸附法对四川省克山病病区30例潜、慢型克山病患者血清中CoxB

关 键 词:克山病  柯萨奇B组病毒  抗体  IGM  IGG  ELISA  血清诊断
修稿时间:2000年9月25日

Detection of Coxsackievirus B specific IgM and IgG of the latent-chronic keshan disease patients
Huang Hanju.Detection of Coxsackievirus B specific IgM and IgG of the latent-chronic keshan disease patients[J].Central China Medical Journal,2001,25(1):5-6.
Authors:Huang Hanju
Abstract:Objective To study the relationship between the infection ofCoxsackieviurs B (CoxB) and the development of keshan disease. Methods Thirty patients with latent-chronic keshan disease in the endemic areas were investigated. The sensitive and specific enzyme linked immunoassay was used to detect CoxB1~6-IgM and CoxB1~6-IgG in the sera from the patients.Results The positive rate for the CoxB1~6-IgM antibody in the latent-chronic keshan patients was significantly higher than that in the control group from non-endemic area (P<0.05). There was no significant difference in CoxB1~6 antibody positive rate between the latent-chronic keshan disease group and the control group from non-endemic area (P>0.05).Conclusion The infection of CoxB existed in endemic area of latent-chronic keshan disease.
Keywords:Keshan disease  Coxsackievirus B  Antibody
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