受压状态下关节软骨胶原纤维结构的电镜观察

目的：观察关节软骨在受压后其胶原纤维结构的形态学变化，方法：对12件人股骨头软骨标本进行分组加载，扫描电镜观察胶原纤维结构，结果：受压后，胶原纤维弯曲，随压力增大而加重，甚至断裂，结论：异常高应力负荷可使关节软骨胶原纤维损伤甚至断裂。

OBSERVING THE COLLAGEN FIBER STRUCTURE IN THE ARTICULAR CARTILARGE UNDER DIFFERENT LOADS BY SCANNING ELECTRON MICROSCOPE

Objective To observe the histomorphlogical changes of the collagen fiber structure after the articular cartilage was subjected to loading. Methods The articular cartilage specimenns from 12 human femoral heads were studied under scanning electronic microscope to observe the structure changes under different sets of loadings. Results The collagen fibers tended to become bended when they were subjected with loadings.The bending of the fiber became more marked and finally disrupted as the loads increased. Conclusion When the articular cartilage is loaded with abnormally high stress,it may result in damage or even cause the disruption of the collagen fibers.