| 微颗粒与急性冠脉综合征 |
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| 引用本文： | 易铁慈,郑乐民,李建平. 微颗粒与急性冠脉综合征[J]. 中国病理生理杂志, 2013, 29(7): 1332-1338. DOI: 10.3969/j.issn.1000-4718.2013.07.033 |
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| 作者姓名： | 易铁慈 郑乐民 李建平 |
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| 作者单位： | 1北京大学第一医院心内科， 北京 100034； 2北京大学医学部心血管所,北京 100191 |
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| 摘 要： |
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| 关 键 词： | 微颗粒 急性冠脉综合征 粥样斑块 血栓形成 |
| 收稿时间： | 2013-01-28 |
Microparticles and acute coronary syndrome |
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| YI Tie-ci , ZHENG Le-min , LI Jian-ping. Microparticles and acute coronary syndrome[J]. Chinese Journal of Pathophysiology, 2013, 29(7): 1332-1338. DOI: 10.3969/j.issn.1000-4718.2013.07.033 |
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| Authors: | YI Tie-ci ZHENG Le-min LI Jian-ping |
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| Affiliation: | 1Department of Cardiology, Peking University First Hospital, Beijing 100034, China;2Institute of Cardiovascular Sciences,Peking University Health Science Center,Beijing 100191,China. |
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| Abstract: | Coronary heart disease (CHD) is an important cause of death in the world. Among them, acute coronary syndrome (ACS) is a type of CHD that has a high mortality rate. Microparticles (MPs) are tiny particles formed in the process of cell activation and apoptosis, carrying specific markers of their mother cells. There is more and more evidence that MPs derived from endothelial cells, platelets, white blood cells and other cells are closely related to the formation of ACS. Through a variety of pathways, they take part in endothelial cell damage, vascular dysfunction, plaque erosion and rupture, and thrombosis. The findings of MPs enrich our knowledge about ACS, and may provide a new approach to the treatment of ACS. |
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| Keywords: | Microparticles Acute coronary syndrome Atherosclerotic plaque Thrombosis |
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