| 阿奇霉素氯化钠注射液中细菌内毒素的检查 |
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| 引用本文： | 文晓玲,刘兴兰,任玺如. 阿奇霉素氯化钠注射液中细菌内毒素的检查[J]. 华西药学杂志, 2004, 19(6): 464-465 |
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| 作者姓名： | 文晓玲 刘兴兰 任玺如 |
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| 作者单位： | 四川省南充市药品检验所,四川,南充,637000;四川省药品检验所,四川,成都,610036 |
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| 摘 要： | 目的建立阿奇霉素氯化钠注射液细菌内毒素的检查方法。方法用不同厂家的鲎试剂对阿奇霉素氯化钠注射液分别进行干扰实验。结果阿奇霉素氯化钠注射液与鲎试剂反应无干扰。结论用细菌内毒素法检查阿奇霉素氯化钠注射液中的内毒素是可行的。
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| 关 键 词： | 阿奇霉素氯化钠注射液 细菌内毒素 鲎试剂 |
| 文章编号： | 1006-0103(2004)06-0464-02 |
| 修稿时间： | 2004-04-01 |
Application of the bacterial endotoxins test for Azithromycin sodium chloride injection |
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| WEN Xiao-ling ,LIU Xing-lan ,REN Xi-ru. Application of the bacterial endotoxins test for Azithromycin sodium chloride injection[J]. West China Journal of Pharmaceutical Sciences, 2004, 19(6): 464-465 |
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| Authors: | WEN Xiao-ling LIU Xing-lan REN Xi-ru |
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| Affiliation: | WEN Xiao-ling 1,LIU Xing-lan 2,REN Xi-ru 1 |
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| Abstract: | OBJECTIVE To establish a method of bacterial test for Azithromycin sodium chloride injection and substitute for the pyrogen test.METHODS TAL made by different factories were used in the inhibition or enhancement tests.RESULTS Azithromycin sodium chloride injection could be directly test by TAL.CONCLUSOIN These results suggested that the bacterial endotoxin test is suitable for the detection of endotoxin in Azithromycin sodium chloride injection. |
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| Keywords: | Azithromycin sodium chloride injection Bcterial endotoxin TAL |
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