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How Do Herbal Medicines Tonify the Kidney and Ameliorate the Marrow Microenvironment Work on Hemopoiesis
作者姓名:Xie  Ren-fu
作者单位:Xie Ren-fu (谢仁敷) ; Liao Jun-xian(廖军鲜) and Ma Rou (麻柔);(China-Japan Friendship Hospital,Beijing) ( 100029)
摘    要:HowDoHerbalMedicinesTonifytheKidneyandAmelioratetheMarrowMicroenvironmentWorkonHemopoiesisXieRen-fu(谢仁敷);LiaoJun-xian(廖军鲜)and...


How Do Herbal Medicines Tonify the Kidneyand Ameliorate the Marrow MicroenvironmentWork on Hemopoiesis
Authors:Xie Ren-fu
Abstract:Herbal Medicines used to tonify Kidney and ameltorate the marrow microenvironmentwere applied in the treatment of 50 patients of aplastic anemia. Stanazol was also used to some cases.Forty-one cases (82. 0 % )responded well. It is significantly better than the 56. 5 % response among thosetreated with stanazol alone. Experimentally, the herbal medicines appear to stimulate hemopoietic pro-genitor cell proliferation, improve the marrow microenyironment and repair marrow damage induced bycyclophosphamide in vivo. The hemopoietic promoting effect might be partly due to the desialation of themarrow stroma cells. The herbal medicines also exert a positive effect on immune system by increasingleukocyte phagocytic activity and elevating the interleukin-2 production. Moreover , the decrease of super-oxide dismutase resulting from cyclophosphamide injection could be reversed by the use of the herbalmedicines. In conclusion, to tonify the Kidney and ameliorate marrow microenvironment medicines pro-duce broad biological results that are beneficial to the body.
Keywords:tonify Kidney  ameliorate marrow microenvironment  herbal medicine  hemopoiesis
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