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Amniotic fluid peptides predict postnatal kidney survival in developmental kidney disease
Authors:Julie Klein  Bénédicte Buffin-Meyer  Franck Boizard  Nabila Moussaoui  Ophélie Lescat  Benjamin Breuil  Camille Fedou  Guylène Feuillet  Audrey Casemayou  Eric Neau  An Hindryckx  Luc Decatte  Elena Levtchenko  Anke Raaijmakers  Christophe Vayssière  Valérie Goua  Charlotte Lucas  Franck Perrotin  Norbert Winer
Affiliation:1. Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institut of Cardiovascular and Metabolic Disease, Toulouse, France;2. Université Toulouse III Paul-Sabatier, Toulouse, France;3. Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium;4. Department of Development and Regeneration, KU Leuven, Leuven, Belgium;5. Department of Obstetrics and Gynecology, Paule de Viguier Hospital, CHU Toulouse, Toulouse, France;6. INSERM, UMR1027, Toulouse, France;7. Prenatal Diagnosis Unit, Poitiers University Hospital, Poitiers, France;8. Pediatrics and Maternity, CHU de Poitiers, Poitiers, France;9. Department of Obstetrics, Gynecology and Fetal Medicine, University Hospital of Tours, Tours, France;10. INSERM, U1253, "Imaging and Brain," François-Rabelais University of Tours, Tours, France;11. Reference Center for Rare Kidney Diseases, Pediatric Nephrology Service, CHRU Clocheville, Tours, France;12. Gynecology-Obstetric Service, AP-HP, Hôpital Antoine Béclère, Université Paris-Sud, Clamart, France;13. Center for Prenatal Diagnosis, Timone Children''s Hospital, Assistance Publique Hopitaux de Marseille, Aix-Marseille Université, Marseille, France;14. Gynecology-Obstetric Service, CHU Clermont-Ferrand, Clermont-Ferrand, France;15. Pediatric Service, CHU Clermont-Ferrand, Clermont-Ferrand, France;16. Department of Gynecology and Obstetrics, CHU de Nantes, Nantes, France;17. Pediatric Nephrology Service, Hôpital Mère-Enfants, CHU Nantes, Nantes, France;18. Department of Obstetrics and Gynecology, University Hospital of Amiens, Amiens, France;19. INSERM, U1105, Picardie Jules Verne University, CHU Amiens, Amiens, France;20. Department of Pediatrics, CHU Nord Amiens, Amiens, France;21. Prenatal Diagnosis, Fondation Lenval, CHU de Nice, Nice, France;22. Clinical Genetics Service, CHU de Saint-Etienne, Saint-Etienne, France;23. Department of Pediatrics, Hôpital Nord, CHU de Saint Etienne, Saint Etienne, France;24. Multidisciplinary Center for Prenatal Diagnosis, CHRU de Brest, Brest, France;25. Department of Pediatrics and Medical Genetics, CHRU Morvan, Brest, France;26. Gynecology-Obstetrics Service, Centre Hospitalier René Dubos, Pontoise, France;27. Pediatric Service, Hôpital Louis Mourier, Colombes, France;28. Pediatric Service, Hôpital Couple-Enfants, CHU Grenoble, Grenoble, France;29. Ultrasound and Foetal Medicine Service of the Department of Gynecology and Obstetrics, Hôpitaux Universitaires de Strasbourg, CMCO, Schiltigheim, France;30. Gynecology-Obstetrics Service, Hôpital Universitaire Robert Debré, APHP, Paris, France;31. Pediatric Nephrology Service, Hôpital Universitaire Robert-Debré, APHP, Paris, France;32. Service de Gynécologie-Obstétrique, Maternité Alix-de-Champagne, CHU de Reims, Reims, France;33. Pediatric Service, Hôpital Américain, CHU Reims, Reims, France;34. Gynecology-Obstetrics Service, l’Hôpital Mère Enfant de Limoges, Limoges, France;35. Gynecology-Obstetrics Service, Hospices Civils de Lyon, Hôpital Femme Mère Enfant, Bron, France;36. Centre de dépistage des Carmes, Toulouse, France;37. Pediatric Clinical Research Unit, Clinical Research Center Toulouse, Hôpital des Enfants, Toulouse, France;38. Department of Pathology, EA 4685, Neuronal Epithelium Interaction Laboratory, Université de Bretagne Occidentale Brest, France;39. Department of Pathology, Children and Mother''s Hospital, Groupement Hospitalier Est, CHU de Lyon-Bron, France;40. Mosaiques Diagnostics and Therapeutics, Hannover, Germany;41. Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK;42. Department of Pediatric Nephrology, Hannover Medical School, Hannover, Germany;43. Center for Developmental Biology (UMR5547) and Center for Integrative Biology (FR 3743), Université de Toulouse, CNRS, UPS, 31062, Toulouse, France;44. INSERM, U1188, Université de La Réunion, Saint-Denis, Réunion;45. Division of Pediatric Nephrology, Heidelberg University Center for Pediatrics and Adolescent Medicine, Heidelberg, Germany;46. Pediatric Nephrology Service, Hôpital des Enfants, CHU Toulouse, Toulouse, France;47. Reference Center for Rare Renal Diseases of the Southwest (SORARE), Toulouse, France;1. Department of Nephrology and Kidney Transplantation, Necker Hospital, Assistance Publique–Hôpitaux de Paris, Paris, France;2. Université de Paris, Paris, France;3. Department of Infectious Diseases and Tropical Medicine, Necker Hospital, Assistance Publique–Hôpitaux de Paris, Paris, France;4. Department of Virology, Necker Hospital, Assistance Publique–Hôpitaux de Paris, Paris, France;1. Sorbonne Université, Université Pierre et Marie Curie Paris 06, Paris, France;2. Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche S1155, Paris, France;3. Division of Nephrology, Department of Internal Medicine Specialties, University Hospital of Geneva, Geneva, Switzerland;4. Centre de Recherche des Cordeliers, Sorbonne Université, INSERM, France;5. Functional Genomics of Solid Tumor, Labex Immuno-Oncology, Equipe Labellisée Ligue Contre le Cancer, Université Paris 13, Paris, France;6. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA;7. Inserm U1151, Necker-Enfants Malades Hospital, Paris, France;8. University Paris Descartes, Sorbonne Paris Cité, Paris, France;9. Department of Adult Nephrology and Transplantation, Necker-Enfants Malades Hospital, Paris, France;10. Department of Nephrology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands;11. Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK;12. Department of Nephrology and Transplantation, University Hospital, Dijon, France;13. BioSpec T Laboratory, EA 7506 URCA, Reims, France;14. Nephropathology Department of Biopathology Laboratory, Reims University Hospital, Reims, France;15. Division of Nephrology, Reims University Hospital, Reims, France;16. Department of Laboratory Medicine and Pathology, Personalized Genomics Laboratory Mayo Clinic, Rochester, Minnesota, USA;17. IntegraGen, Evry, France;18. Transplant Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic;19. Department of Transplantation, Nephrology, and Clinical Immunology, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France;20. Laboratoire HLA, Etablissement Français du Sang Auvergne Rhone-Alpes, Lyon, France;21. Nephrology Department, Hospital Universitari Bellvitge, Bellvitge Research Institute (IDIBELL), Barcelona, Spain;22. RedInRen, RD16/0009/0031, University of Barcelona, L’Hospitalet de Llobregat, Barcelona, Spain;23. Hospital Universitario de Canarias, Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, Tenerife, Spain;24. Division of Transfusion Medicine, Mayo Clinic, Rochester, Minnesota, USA;25. Department of Nephrology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic;26. Department of Nephrology, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic;27. Department of Nephrology, University Hospital, Nantes, France;28. Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche S 1109, Strasbourg University, Strasbourg, France;29. Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France;30. Department of Nephrology, Strasbourg University Hospital, Strasbourg, France;31. Université de Reims Champagne-Ardenne, CNRS UMR 7369 (Matrice Extracellulaire et Dynamique Cellulaire, MEDyC), Reims, France;32. Department of Nephrology, University Hospital, Amiens, France;33. Department of Nephrology, Fundación Puigvert, Barcelona, Spain;34. Department of Nephrology (Day Hospital), AP-HP, Tenon Hospital, Paris, France;1. Department of Pediatrics, Division of Nephrology, University of Michigan, C S Mott Children’s Hospital, Ann Arbor, Michigan, USA;2. NephCure Kidney International, King of Prussia, Pennsylvania, USA;3. Department of Pediatrics, Division of Nephrology, "Bambino Gesù" Pediatric Hospital–Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy;4. Department of Pediatrics, Division of Nephrology, University Hospitals Leuven, Katholieke Universiteit Leuven, Leuven, Belgium;5. Department of Pediatrics, Division of Nephrology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;6. Department of Pediatrics, Division of Nephrology, Ohio State University, Nationwide Children’s Hospital, Columbus, Ohio, USA;7. Department of Pediatrics, Division of Nephrology, New York University Grossman School of Medicine, New York, New York, USA;1. Division of Nephrology, Department of Internal Medicine, International University of Health and Welfare School of Medicine, Shizuoka, Japan;1. Diabetes Center, Internal Medicine, Amsterdam UMC, Location VUmc, Amsterdam, the Netherlands;2. Department of Medicine, Division of Nephrology, University of Colorado School of Medicine, Aurora, Colorado, USA;3. Section of Endocrinology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA;4. Department of Clinical Pharmacy and Pharmacology, University of Groningen, Groningen, the Netherlands;5. Steno Diabetes Center Copenhagen, Copenhagen, Denmark;6. Division of Nephrology, University of Toronto, Toronto, Canada;1. Division of Nephrology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;2. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA;3. Division of Nephrology, Yonsei University Wonju College of Medicine, Wonju, Gangwon, South Korea;4. Division of Nephrology, Huashan Hospital, Wudan University, Shanghai, China;5. Division of Pediatric Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee, USA;6. Institute of Medical Science, Tokai University, Isehara, Japan;7. Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA;8. Departments of Medicine, Cancer Biology, and Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA;9. Medicine and Research Services, Department of Veterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville, Tennessee, USA
Abstract:
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  • Keywords:amniotic fluid  congenital anomalies of the kidney and the urinary tract  infants  management  peptides  prediction  termination of pregnancy
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