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Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis
Authors:Helen He  Robert Bissonnette  Jianni Wu  Aisleen Diaz  Etienne Saint-Cyr Proulx  Catherine Maari  Carolyn Jack  Maudeline Louis  Yeriel Estrada  James G Krueger  Ning Zhang  Ana B Pavel  Emma Guttman-Yassky
Institution:1. Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY;2. Laboratory of Investigative Dermatology, The Rockefeller University, New York, NY;3. Innovaderm Research, Montreal, Quebec, Canada;4. State University of New York Downstate Medical Center, College of Medicine, New York, NY;5. Ponce Health Sciences University School of Medicine, Ponce, Puerto Rico
Abstract:
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  • Keywords:Atopic dermatitis  psoriasis  tape strips  biomarker  skin  RNA sequencing  immune  epidermal barrier  AD"}  {"#name":"keyword"  "$":{"id":"kwrd0070"}  "$$":[{"#name":"text"  "_":"Atopic dermatitis  AUC"}  {"#name":"keyword"  "$":{"id":"kwrd0080"}  "$$":[{"#name":"text"  "_":"Area under the curve  CCL"}  {"#name":"keyword"  "$":{"id":"kwrd0090"}  "$$":[{"#name":"text"  "_":"C-C motif chemokine ligand  CXCL"}  {"#name":"keyword"  "$":{"id":"kwrd0100"}  "$$":[{"#name":"text"  "_":"C-X-C motif chemokine ligand  DC"}  {"#name":"keyword"  "$":{"id":"kwrd0110"}  "$$":[{"#name":"text"  "_":"Dendritic cell  DEG"}  {"#name":"keyword"  "$":{"id":"kwrd0120"}  "$$":[{"#name":"text"  "_":"Differentially expressed gene  FCH"}  {"#name":"keyword"  "$":{"id":"kwrd0130"}  "$$":[{"#name":"text"  "_":"Fold change  FDR"}  {"#name":"keyword"  "$":{"id":"kwrd0140"}  "$$":[{"#name":"text"  "_":"False discovery rate  IGA"}  {"#name":"keyword"  "$":{"id":"kwrd0150"}  "$$":[{"#name":"text"  "_":"Investigator's Global Assessment  iNOS"}  {"#name":"keyword"  "$":{"id":"kwrd0160"}  "$$":[{"#name":"text"  "_":"Inducible nitric oxide synthase  LCE"}  {"#name":"keyword"  "$":{"id":"kwrd0170"}  "$$":[{"#name":"text"  "_":"Late cornified envelope  NOS"}  {"#name":"keyword"  "$":{"id":"kwrd0180"}  "$$":[{"#name":"text"  "_":"Nitric oxide synthase  PGA"}  {"#name":"keyword"  "$":{"id":"kwrd0190"}  "$$":[{"#name":"text"  "_":"Physician's Global Assessment  qRT-PCR"}  {"#name":"keyword"  "$":{"id":"kwrd0200"}  "$$":[{"#name":"text"  "_":"Quantitative real-time polymerase chain reaction  RNA-seq"}  {"#name":"keyword"  "$":{"id":"kwrd0210"}  "$$":[{"#name":"text"  "_":"RNA sequencing  TLSS"}  {"#name":"keyword"  "$":{"id":"kwrd0220"}  "$$":[{"#name":"text"  "_":"Target Lesion Symptom Score  TSS"}  {"#name":"keyword"  "$":{"id":"kwrd0230"}  "$$":[{"#name":"text"  "_":"Total Sign Score
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