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A well-developed endolysosomal system reflects protein reabsorption in segment 1 and 2 of rat proximal tubules
Authors:Erik I Christensen  Inger B Kristoffersen  Birgitte Grann  Jesper S Thomsen  Arne Andreasen  Rikke Nielsen
Institution:1. Department of Biomedicine, Anatomy, Aarhus University, Aarhus, Denmark;1. Nanjing Key Laboratory of Pediatrics, Children’s Hospital of Nanjing Medical University, Nanjing, China;2. Jiangsu Key Laboratory of Pediatrics, Nanjing Medical University, Nanjing, China;3. Department of Nephrology, State Key Laboratory of Reproductive Medicine, Children’s Hospital of Nanjing Medical University, Nanjing, China;4. Renal Division, Peking University First Hospital, Beijing, China;1. CHU de Québec Research Center, Québec City, Québec, Canada;2. Division of Nephrology, Department of Medicine, Faculty of Medicine, Université Laval, Québec City, Québec, Canada;1. Inserm Unit 1018, Team 5, CESP, Hôpital Paul Brousse, Paris-Sud University and Versailles Saint-Quentin-en-Yvelines University (Paris-Ile-de-France-Ouest University, UVSQ), Villejuif, France;1. Department of Physiology, Amsterdam University Medical Centers, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands;2. Department of Clinical Chemistry, Amsterdam University Medical Centers, Amsterdam, The Netherlands;3. Department of Nephrology, Amsterdam University Medical Centers, Amsterdam, The Netherlands;4. Department of Physiology, Maastricht University, Maastricht, The Netherlands;1. Division of Nephrology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China;2. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA;3. Division of Nephrology, Yonsei University Wonju College of Medicine, Wonju, Gangwon, South Korea;4. Division of Nephrology, Huashan Hospital, Wudan University, Shanghai, China;5. Division of Pediatric Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee, USA;6. Institute of Medical Science, Tokai University, Isehara, Japan;7. Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA;8. Departments of Medicine, Cancer Biology, and Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA;9. Medicine and Research Services, Department of Veterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville, Tennessee, USA
Abstract:
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  • Keywords:megalin  protein reabsorption  proximal tubule  segments
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