Potential mechanisms of anaphylaxis to COVID-19 mRNA vaccines |
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| Authors: | Kimberly A. Risma Kathryn M. Edwards Donna S. Hummell Frederic F. Little Allison E. Norton Amy Stallings Robert A. Wood Joshua D. Milner |
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| Affiliation: | 1. Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio;2. Division of Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tenn;3. Division of Pediatric Allergy, Immunology, and Pulmonary Medicine, Department of Pediatrics, Monroe Carell Jr. Children’s Hospital at Vanderbilt, Vanderbilt University School of Medicine, Nashville, Tenn;4. Division of Pulmonary, Allergy, Sleep and Critical Care Medicine, Department of Pediatrics, Boston University School of Medicine, Boston, Mass;5. Division of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC;6. Division of Pediatric Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, Md;7. Department of Pediatrics, Columbia University Irving Medical Center, New York, NY |
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| Abstract: | |
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| Keywords: | COVID-19 vaccine mRNA vaccine anaphylaxis allergy polyethylene glycol PEGylated liposome lipid nanoparticle mast cells BAT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" Basophil activation test BST" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" Basal serum tryptase C3a" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" Complement component 3a C5a" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" Complement component 5a COVID-19" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" Coronavirus disease 2019 DC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0105" }," $$" :[{" #name" :" text" ," _" :" Dendritic cell Fc" },{" #name" :" keyword" ," $" :{" id" :" kwrd0115" }," $$" :[{" #name" :" text" ," _" :" Fragment crystallizable region HMW" },{" #name" :" keyword" ," $" :{" id" :" kwrd0125" }," $$" :[{" #name" :" text" ," _" :" High-molecular-weight LNP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0135" }," $$" :[{" #name" :" text" ," _" :" Lipid nanoparticle mRNA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0145" }," $$" :[{" #name" :" text" ," _" :" Messenger RNA PEG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0155" }," $$" :[{" #name" :" text" ," _" :" Polyethylene glycol PEGylated" },{" #name" :" keyword" ," $" :{" id" :" kwrd0165" }," $$" :[{" #name" :" text" ," _" :" Polyethlene glycol conjugated |
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