Non-Hodgkin Lymphoma Mimicking Endodontic Lesion: A Case Report with 3-dimensional Analysis,Segmentation, and Printing |
| |
Authors: | Ali Nosrat Prashant Verma Sarah Glass Craig E. Vigliante Jeffery B. Price |
| |
Affiliation: | 1. Division of Endodontics, Department of Advanced Oral Sciences and Therapeutics, University of Maryland, Baltimore, Maryland;2. Private Practice, Centerville Endodontics, Centreville, Virginia;3. Department of Oral Diagnostic Sciences, School of Dentistry, Virginia Commonwealth University, Richmond, Virginia;4. Private Practice, Potomac Surgical Arts, PC, Leesburg, Virginia;6. Reston Advanced Oral and Cosmetic Facial Surgery, LLC, Reston, Virginia;5. Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, Maryland |
| |
Abstract: | Non-Hodgkin lymphoma (NHL) of the oral cavity can present with pain, swelling and radiolucent lesion mimicking endodontic diseases. This article reports on a case of diffuse large B-cell lymphoma initially diagnosed and treated as periodontal disease and then endodontic disease in the maxillary anterior and premolar area of a 40-year old female. A cone beam computed tomography (CBCT) image of the lesion was taken. The lesion was segmented using Mimics software (Materialise NV, Lueven, Belgium). Three-dimensional models of the tumor were printed. During the surgical phase teeth #4, 6, and 7 were extracted and biopsy samples were obtained. Histopathologic examination showed invasive sheets of large, atypical, basophilic cells strongly and diffusely positive for CD20. Three-dimensional analysis, segmentation, and printing of radiolucent lesions of the jaws assists with differential diagnosis and efficient treatment. Oral health professionals can play a crucial role in the early detection and diagnosis of oral NHL, thereby preventing extensive loss of function and esthetics, and even saving lives. |
| |
Keywords: | 3-Dimensional printing cancer cone-beam computed tomography diffuse large B-cell lymphoma non-Hodgkin lymphoma segmentation |
本文献已被 ScienceDirect 等数据库收录! |
|