脑梗死患者血清神经元烯醇化酶测定的临床价值

目的　探讨脑梗死患者血清神经元烯醇化酶 (NSE)与脑梗死灶大小和临床预后的关系。方法　采用酶联免疫吸附法对 39例脑梗死患者起病第 1、3、7天血清NSE水平进行了动态测定。结果　脑梗死患者血清NSE浓度在起病第 1、3天显著高于对照组 (P <0 .0 1) ,第 3天达峰值 ,峰值浓度与梗死灶大小及临床预后有显著相关性。结论　血清NSE水平测定对判断脑梗死病变的严重程度、估价预后有重要参考价值

Meaurment of Neurone Specific Enolase in Patients with Cerebral Infaction and Its Clinical Value

Objective To investigate the clinical relevance of serum level of neurone specific enolase (NSE) in patients with cerebral infarction.Methods Using sandwich immunoassays,serum level of NSE was measured at day 1,day 3 and day 7 after infarction in 39 patients.Results The level of NSE was significantly increased at day 1 and day 3 ( P <0.01),it peaked at day 3.The peak of NSE was significantly correlated with the volume of infarction and clinical outcome.Conclusion It is believed that measurement of NSE is useful in the assessment of severity and the prediction of clinical outcome in patients with cerebral infarction.