郑州地区亚健康人群中医基本证候的流行病学研究

目的研究亚健康人群的临床表现及其中医基本证候分布特征。方法通过大量文献调研，建立“亚健康状态”知识型数据库，结合流行病学、计算机学、数学、国际量表学等有关原则，依据GB／T1．1—2000和ZY／T001．1-94标准表述方法，拟定《亚健康基本证候调查表》，通过对郑州地区亚健康人群的流行病学调查，应用多因素分析和聚类分析等数理统计方法，探讨亚健康状态主要症状及证候分布。结果对2133份亚健康调查数据分析结果表明，郑州地区亚健康人群以畏寒、疲乏、自汗、记忆差、易怒、气短、心悸等症状群为主要临床表现；以虚、湿、痰、郁、瘀、气滞、津亏等为主要证候要素；脏腑功能失调多见于心、脾、肾、肝、胆、胃、肺等；以心脾两虚、心肾两虚、肝郁气滞、脾虚湿困、痰气互结、肾阴虚、肾阳虚、气虚证、肝郁化火、湿热蕴结等基本证候多见。结论亚健康人群的临床表现呈现某一症状为主，其他症状伴随出现的症状群，基本证候分布以虚证为主。

Epidemiologic Study on Basic TCM Syndrome in the Subhealth Population in the Zhengzhou Area

OBJECTIVE: To study the distribution characteristics of clinical manifestation and TCM basic syndromes in the subhealth population. METHODS: The investigation list for basic syndrome of subhealth used in the study was formulated through retrieving a large amount of literatures, referring to principles of epidemiology, computer science, mathematics and international metrics, and according to the standard denoting figure of GR/T 1.1-2000 and ZY/T001.1-94. The data obtained were analyzed by the statistical methods like multiple factor analysis and cluster analysis to explore the distribution of main symptoms and syndromes in the subhealth condition. RESULTS: The analysis of data from 2,133 lists showed that in the Zhengzhou area, the main clinical symptoms presented in the subhealth population were aversion to cold, fatigue, spontaneous perspiration, poor memory, bad-temper, short breath, palpitation, etc.; with the syndrome key elements of deficiency, dampness, phlegm, stagnancy, stasis, qi-stagnation, and body fluid loss; the dysfunction of zang-fu organs was mainly observed in Xin, Pi, Shen, Gan, Dan, Wei, Fei, etc.; and the most commonly encountered basic syndromes were Xin-Pi deficiency, Xin-Shen deficiency, Gan-qi stagnation, Pi insufficiency with dampness stagnation, phlegm-qi cementation, Shen-yin deficiency, Shen-yang deficiency, qi insufficiency, Gan-stagnancy transforming to fire, damp-heat accumulation, etc. CONCLUSION: The clinical manifestation of the subhealth population in the Zhengzhou area is characterized by a syndrome composed of a certain main symptom with some other accompanied symptoms, the distribution of the basic syndrome is mainly dominated by the deficiency syndrome.