长期住院老年患者真菌感染相关危险因素分析

目的 探讨长期住院老年患发生真菌感染的原因。方法 对某院2000年3月～2003年3月间发生真菌感染的168例老年患和30例同期住院未发生真菌感染的老年患的临床资料进行回顾性对比分析。结果 患有严重基础疾病、长期应用抗菌药物、气管切开及机械通气、呼吸道分泌物引流不畅、留置胃管及使用免疫抑制剂等因素是老年患发生真菌感染的主要危险因素。结论 老年患易发生呼吸道真菌感染，在积极治疗原发病的基础上，合理用药、改善某些医护行为是预防、控制真菌感染的关键。

Risk factors for infection with fungi in long term hospitalization old patients

Objective To analyze risk factors for infection with fungi in long term hospitalization old patients. Methods Clinical data of 168 patients with fungi infection and 30 patients without fungi infection from March, 2000 to March, 2003 hospilization period were compared and analysed retrospectively. Results The main factors for infection with fungi in old patents were severe underlying diseases, long term antimicrobial application, tracheotomy, mechanical ventilation, poor drainage of respiratory secretion, indwelling gastric tube and use of immunosuppressant. Conclusion Old patients are susceptible to respiratory fungi infection, on the basis of treating underlying diseases, the key to prevent and control fungi infection is the rational use of antimicrobial agents and improvement of medical practice.