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杏贝止咳祛痰口服液辅助治疗小儿支气管肺炎
引用本文:常丽,李尔珍,张奕. 杏贝止咳祛痰口服液辅助治疗小儿支气管肺炎[J]. 中国实验方剂学杂志, 2013, 19(18): 320-322
作者姓名:常丽  李尔珍  张奕
作者单位:首都儿科研究所附属儿童医院,北京,100020
基金项目:2013年首都儿科研究所所内课题(所13年B08)
摘    要:目的:观察杏贝止咳祛痰口服液辅助治疗小儿支气管肺炎的疗效.方法:90例支气管肺炎住院患儿,随机分成两组,治疗组47例给予支气管肺炎常规治疗(依病原菌选择给予头孢或阿奇霉素治疗,病毒性肺炎不给予抗生素,合并喘息患儿给予复方异丙托溴胺雾化治疗)的基础上,加用杏贝止咳祛痰口服液口服.对照组43例仅给予常规治疗.7d为1个疗程,观察患儿体温、咳嗽、肺部体征变化、疾病转归及住院天数.结果:治疗组患儿咳嗽明显好转(咳嗽频率减低>50%)时间及住院天数均短于对照组,患儿体温降至正常的时间及肺部体征消失的时间均短于对照组(P>0.05).治疗组患儿总有效率高于对照组(P<0.05),未愈率低于对照组.治疗组不良反应发生率低于对照组(P>0.05).结论:杏贝止咳祛痰口服液辅助治疗小儿支气管肺炎可以缩短患儿症状和肺部体征恢复时间及住院天数,提高治疗的有效性,未见明显不良反应.

关 键 词:支气管肺炎  杏贝止咳祛痰口服液  小儿
收稿时间:2013-01-14

Study of Therapeutic Effect and Hospital Duration of Xingbei Zhike Qutan Oral Liquid on Children with Pneumonia
CHANG Li,LI Er-zhen and ZHANG Yi. Study of Therapeutic Effect and Hospital Duration of Xingbei Zhike Qutan Oral Liquid on Children with Pneumonia[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(18): 320-322
Authors:CHANG Li  LI Er-zhen  ZHANG Yi
Affiliation:Capital Institute of Pediatrics Affiliated Hospital, Beijing 100020, China;Capital Institute of Pediatrics Affiliated Hospital, Beijing 100020, China;Capital Institute of Pediatrics Affiliated Hospital, Beijing 100020, China
Abstract:Objective: To evaluate the therapeutic effect and hospital duration of Xingbei Zhike Qutan oral liquid on children with pneumonia. Method: Ninty hospitalized children with pneumonia were rando mLy divided into two groups. Treatment group was treated with Xingbei Zhike Qutan oral liquid based on routine treatment(Cephalosporin to bacterial pneumonia, Azithromycin to Mycoplasma pneumonia, no antibiotics to viral pneumonia and Compound Ipratropium Bromide Aerosol to children with wheezing), control group was treated only with routine treatment without any oral drugs. The treatment duration was 7 days. The cough, temperature, chest sighs, hospital duration and therapeutic effect were evaluated. Result: The average time of cough relief and average hospital duration were significantly shorter than in control group. The average time of chest signs disappearing and falling to normal temperature in treatment group was shorter than in control group.The total effective rate in treatment group was significantly higher than that in control group (P<0.05), and the non-effective rate was lower than that in control group.There was no difference in side-effect rate between treatment group and control group. Conclusion: Xingbei Zhike Qutan oral liquid shortens the improved time of symptoms and chest signs, increases the total effective rate, shortens the hospital duration of children with pneumonia and has no adverse reaction.
Keywords:pneumonia  Xingbei Zhike Qutan oral liquid  child
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