| 星点设计-效应面法优化陈皮多糖提取工艺 |
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| 引用本文： | 刘荣,韦正,银玲,樊丹青,杨丽,陈鸿平,刘友平. 星点设计-效应面法优化陈皮多糖提取工艺[J]. 中国实验方剂学杂志, 2013, 19(18): 23-26 |
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| 作者姓名： | 刘荣 韦正 银玲 樊丹青 杨丽 陈鸿平 刘友平 |
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| 作者单位： | 成都中医药大学药学院, 中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 成都 611137;成都中医药大学药学院, 中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 成都 611137;成都中医药大学药学院, 中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 成都 611137;成都中医药大学药学院, 中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 成都 611137;成都中医药大学药学院, 中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 成都 611137;成都中医药大学药学院, 中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 成都 611137;成都中医药大学药学院, 中药资源系统研究与开发利用省部共建国家重点实验室培育基地, 成都 611137 |
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| 基金项目： | 国家自然科学基金项目(81072991);四川省教育厅自然科学重点项目(09ZA033) |
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| 摘 要： | 目的: 采用星点设计-效应面法优化陈皮多糖的提取工艺。方法: 在单因素试验基础上,选取料液比、提取温度、提取时间为自变量,陈皮多糖提取率为因变量,利用星点设计模型对3个自变量各水平二项式进行拟合,确定陈皮多糖的最佳提取工艺。结果: 优选的提取工艺为料液比1:49,提取温度92 ℃,回流提取时间150 min,陈皮多糖提取率达14.77%,与预测值的偏差0.61%。结论: 星点设计-效应面法优化的陈皮多糖提取工艺简便可靠,为陈皮多糖的开发利用奠定基础。
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| 关 键 词： | 陈皮 多糖 星点设计-效应面法 提取工艺 |
| 收稿时间： | 2013-02-27 |
Optimization of Extraction Technology for Polysaccharides from Citri Reticulatae Pericarpium by Central Composite Design-Response Surface Methodology |
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| LIU Rong,WEI Zheng,YIN Ling,FAN Dan-qing,YANG Li,CHEN Hong-ping and LIU You-ping. Optimization of Extraction Technology for Polysaccharides from Citri Reticulatae Pericarpium by Central Composite Design-Response Surface Methodology[J]. China Journal of Experimental Traditional Medical Formulae, 2013, 19(18): 23-26 |
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| Authors: | LIU Rong WEI Zheng YIN Ling FAN Dan-qing YANG Li CHEN Hong-ping LIU You-ping |
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| Affiliation: | College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Co-constructioned by Ministry of Science and Technology of the People's Republic of China and Sichuan Province, Chengdu 611137, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Co-constructioned by Ministry of Science and Technology of the People's Republic of China and Sichuan Province, Chengdu 611137, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Co-constructioned by Ministry of Science and Technology of the People's Republic of China and Sichuan Province, Chengdu 611137, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Co-constructioned by Ministry of Science and Technology of the People's Republic of China and Sichuan Province, Chengdu 611137, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Co-constructioned by Ministry of Science and Technology of the People's Republic of China and Sichuan Province, Chengdu 611137, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Co-constructioned by Ministry of Science and Technology of the People's Republic of China and Sichuan Province, Chengdu 611137, China;College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Breeding Base of State Key Laboratory of Resources System Research and Development Utilization of Chinese Herbal Medicines Co-constructioned by Ministry of Science and Technology of the People's Republic of China and Sichuan Province, Chengdu 611137, China |
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| Abstract: | |
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| Keywords: | Citri Reticulatae Pericarpium polysaccharides central composite design-response surface methodology extraction process |
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