身痛逐瘀汤加减治疗腰椎间盘突出症近期疗效观察

目的:观察身痛逐瘀汤加减治疗腰椎间盘突出症(LDH)的近期疗效.方法:120例LDH患者随机按数字法分为对照组和观察组各60例.对照组给予壮医药线点灸,观察组给予身痛逐瘀汤加减联合壮医药线点灸,疗程均为20 d.记录治疗前及治疗后第2、4、6、8、10、12、14、20天疼痛VAS评分,并计算疼痛改善率；记录治疗前、后和随访期疼痛量表(包括疼痛分级指数、视觉模拟量表、现时疼痛强度)和Oswestry功能障碍指数的变化情况,并检测血浆β-内啡肽(β-EP)水平.结果:观察组总有效率93.33％,优于对照组的78.33％ (P ＜0.05)；两组治疗后VAS评分均呈下降趋势,第6天至疗程结束,观察组VAS评分均低于对照组(P ＜0.05或P＜0.01)；治疗后第7、14、20天观察组疼痛改善率均优于对照组(P＜0.05或P＜0.01)；治疗后及随访期观察组腰椎间盘突出症(SF-MPQ)各项评分及Oswestry功能障碍指数均低于同期对照组(P＜0.01)；治疗后及随访期观察组血浆β-EP水平均高于对照组(P＜0.01).结论:身痛逐瘀汤加减治疗腰椎间盘突出症能明显减轻患者疼痛,改善患者功能障碍,提高血浆β-EP水平,近期疗效显著.

Shentong Zhuyu Decoction Add-subtract on the Treatment of Lumbar Disc Herniation Curative Effect Observation

Objective: Observation of shentong zhuyu decoction Add-Subtract in the treatment of lumbar disc herniation (LDH) efficacy. Method: One hundred and twenty cases of LDH were randomly allocated to experimental and control groups according to random number table, 60 cases in each group. The control groups were treatedf with Zhuang medicine medicated thread moxibustion while the experimental were added with Shentong Zhuyu decoction, both lasting for 20 days. Different time points of the 0, 2, 4,6,8,10,12,14,20^th day were followed measuring the visual analogue scale pain scales and its improvement rate, brief pain scales including pain and Oswestry function index. Result: Overall effectiveness of experimental group with 93.33% was better than control group with 78.33%(P<0.05);VAS of both groups was in decrease from the 6^th day to the end of the treatment. VAS of the experimental was lower than that of the control(P<0.05 or P<0.01);the improvement rates of pain of experiment at the 7, 14,20 day were better than the control(P<0.05 or P<0.01); the SF-MPQ scores and Oswestry function index of the experimental were all lower than the control groups in the first and the second visit point (P<0.01). Conclusion: Shentong Zhuyu decoction Add-Subtract on the treatment of lumbar disc herniation can significantly reduce the pain of patients, improve patient function, significant short-term effect, is worthy to be popularized.