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Concentration-effect relations of glibenclamide and its active metabolites in man: modelling of Pharmacokinetics and Pharmacodynamics |
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| Authors: | T. Rydberg ,A. Jö nsson,M. O. Karlsson,& A. Melander |
| Affiliation: | The Hospital Pharmacy, Central Hospital, Kristianstad, and Department of Clinical Pharmacology, Lund University, Lund, Sweden, ,;Department of Endocrinology, Lund University, MalmöUniversity Hospital, Malmö, Sweden, ,;Department of Pharmacy, Division of Biopharmaceutics and Pharmacokinetics, Biomedical Centre, Uppsala University, Uppsala, Sweden, ,;The NEPI Foundation, Medical Research Centre, MalmöUniversity Hospital, Malmö, Sweden. |
| Abstract: | |
| Keywords: | glibenclamide metabolites sulphonylurea diabetes mellitus non-insulin dependent pharmacokinetics pharmacodynamics pharmacodynamic modelling glucose |