Enhanced expression of sarcoplasmic reticulum Ca2+-ATPase gene plays a role in protective effects of nitric oxide |
| |
| Authors: | N. P. Aimasheva E. B. Malenyuk E. B. Manukhina G. L. Khaspekov V. D. Mikoyan L. N. Kubrina A. F. Vanin I. Yu. Malyshev |
| |
| Affiliation: | (1) Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow;(2) Russian Cardiology Research-and-Production Complex, Ministry of Health of the Russian Federation, Moscow;(3) Institute of Chemical Physics, Russian Academy of Science, Moscow |
| |
| Abstract: | This study verifies the hypothesis that NO-dependent regulation of sarcoplasmic reticulum Ca2+-ATPase gene (SERCA) plays an important role in preventing Ca2+ overload after exposure to damaging factors. The data confirmed NO-dependent activation of SERCA expression and important role of this mechanism in the reduction of calcium overload. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol 128, No. 10, pp. 375–379, October, 1999 |
| |
| Keywords: | nitric oxide Ca2+-ATPase expression reperfusion physical exercise |
| 本文献已被 SpringerLink 等数据库收录！ |
|
