Antibodies to lipid A in pauciarticular juvenile arthritis: clinical studies. |
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| Authors: | J J Miller L C Olds |
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| Affiliation: | Children's Hospital, Stanford University School of Medicine, CA. |
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| Abstract: | IgG antibodies to monophosphoryl lipid A (MPL) are more concentrated in synovial fluids than in the blood of children with pauciarticular juvenile arthritis. Correlations between IgG anti-MPL levels and numbers of inflamed joints were highly significant in 2 of 10 patients followed for 8 years and suggestive in 2 patients followed for shorter periods. A fifth patient had a correlation between IgM anti-MPL and joint count. |
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