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复方黄黛片与化疗交替应用对急性早幼粒细胞白血病患者长期生存的影响
引用本文:向阳,黄世林,郭爱霞,魏艾红,张励,孙淑君,陈楠楠,成玉斌,王丹. 复方黄黛片与化疗交替应用对急性早幼粒细胞白血病患者长期生存的影响[J]. 临床血液学杂志, 2003, 16(5): 204-206
作者姓名:向阳  黄世林  郭爱霞  魏艾红  张励  孙淑君  陈楠楠  成玉斌  王丹
作者单位:解放军第210医院中医血液科,解放军第210医院中医血液科,解放军第210医院中医血液科,解放军第210医院中医血液科,解放军第210医院中医血液科,解放军第210医院中医血液科,解放军第210医院中医血液科,解放军第210医院中医血液科,解放军第210医院中医血液科 辽宁 大连,116021,辽宁 大连,116021,辽宁 大连,116021,辽宁 大连,116021,辽宁 大连,116021,辽宁 大连,116021,辽宁 大连,116021,辽宁 大连,116021,辽宁 大连,116021
摘    要:目的:探讨复方黄黛片与化疗交替应用对急性早幼粒细胞白血病(APL)患者长期生存的影响。方法:采用复方黄黛片与化疗交替应用治疗APL患者62例。结果:中位缓解期为48个月;仍在随访并配合治疗的54例患者中,3、5、7、10年的无复发生存率(RFS)分别为68.41%、48.15%、38.89%和18.52%;3年生存概率为88.52%,5、7、lO年生存概率均为86.88%。结论:复方黄黛片与化疗交替应用是有效可行的缓解后的治疗方案。

关 键 词:白血病 早幼粒细胞 急性 化学疗法 中药制剂 长期生存
文章编号:1004-2806(2003)05-0204-03
修稿时间:2003-02-12

The influence on long-term survey of the patients with acute promyelocytic leukemia treated alternatively with compound huangdai tablets and chemotherapy
XIANG Yang HUAG Shilin GUO Aixia WEI Aihong ZHANG LiSUN Shujun CHEN Nannan CHEN Yubin WAN Dan. The influence on long-term survey of the patients with acute promyelocytic leukemia treated alternatively with compound huangdai tablets and chemotherapy[J]. Journal of Clinical Hematology, 2003, 16(5): 204-206
Authors:XIANG Yang HUAG Shilin GUO Aixia WEI Aihong ZHANG LiSUN Shujun CHEN Nannan CHEN Yubin WAN Dan
Abstract:Objective:To investigate the influence on long-term survey of the patients with acute promyelocytic leukemia treated alternatively with compound huangdai tablets and chemotherapy. Method:Sixty-two patients were treated alternatively with compound huangdai tablets and chemotherapy. Result:The median time of complete remission was 48 months. Among the patients who are followed-up and persistent to treat, 3- ,5- ,7 - and 10-year relapse-free survival (RFS)were 68. 41% ,48. 15% ,38. 89% ,18. 52% respectively, and 3-year survival probability was 88. 52% ,5- ,7 -and 10 -year survival probability were 86. 88%. Conclusion:Compound huangdai tablets and chemotherapy is an effective treatment protocol post-remission.
Keywords:Leukemia   promyelocytic   acute  Chemotherapy  Chinese traditional medicine  Long-term survey
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