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安坦治疗癫痫的疗效观察(附40例分析)
引用本文:郝培来,聂成福,李松奎. 安坦治疗癫痫的疗效观察(附40例分析)[J]. 山东医学高等专科学校学报, 1989, 0(4)
作者姓名:郝培来  聂成福  李松奎
作者单位:沂水中心医院内科,沂水中心医院内科,沂水中心医院内科 1977年毕业生
摘    要:安坦治疗各型癫痫40例,总有效率82.5%,EEG有相应的改善,其中对大发作疗效较好,育效率87.1%。剂量4~12mg/d,成人一般不超过18mg/d为宜。副作用少,个别病人有口渴,眼干及一过性头晕。其作用机理可能与其对抗中枢介质Ach的作用,降低网状-丘脑及丘脑-皮质投射系统的兴奋性有关。

关 键 词:安坦  癫痫  癫痫  大发作  癫痫  颞叶性  癞痫  小发作

OBSERVATION OF THERAPEUTIC EFFECTS OF ARTANE IN TREATMENT OF EPILEPSY
Hao Peilai et al Dept.of Internal Medicine,Yishui Central Hospital,Shandong. OBSERVATION OF THERAPEUTIC EFFECTS OF ARTANE IN TREATMENT OF EPILEPSY[J]. Journal of Shandong Medical College, 1989, 0(4)
Authors:Hao Peilai et al Dept.of Internal Medicine  Yishui Central Hospital  Shandong
Abstract:Forty cases with different types of epilepsy treated with Antan are reported. The total effective rate was 82.5% with EEG improved. Especially the efficacy in the patients with grandmal epilepsy was better with the effective rate of 87.1%. The dose was 4-12mg/d. As to the adults, the dose was no more than 18mg/d, having less side effect. Some patients had the appearence of thirst, xerophthalmia or temporary dizziness. The mechanism of the drug might be related to the effect of anti-central mediate Ach, which might depress the excitability of the reticula-thalamsncephalon and thalamencephalon-cortical projection system.
Keywords:Artane  Epilepsy  Epilepsy   grandmal  Epilepsy  temporal Iobe  Epilepsy   petit maI
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