高血压病患者左室几何结构与二尖瓣血流频谱的关系

目的探讨高血压病患者左室几何结构与二尖瓣血流参数的关系。方法应用脉冲多普勒测量60例高血压病患者及30例正常人二尖瓣血流参数，采用M型超声心动图测量其相对室壁厚度(relative wall thickness，RWT)，以正常人RWT值均数加二倍标准差将高血压病患者分为RWT正常组与RWT增大组。结果早期充盈参数(peak flow velocity，Peak E；deceleration half-time，DHT)在高血压病两组间差异显著。相关分析表明高血压病患者RWT与PeakE、DHT相关良好；而左室质量则与PeakE、DHT相关不良。结论高血压病患者RWT对其早期充盈参数PeakE、DHT有较为明显的影响。

INFLUENCE OF RELATIVE WALL THICKNESS ON THE PATTERNS OF LEFT VENTRICULAR FILLING IN PATIENTS WITH HYPERTENSION

ObjectiveTo determine whether the patterns of left ventricular filling may be influenced by the relative wall thickness(RWT) in arterial hypertension.MethodsThe transmitral blood flow parameters and the RWT were evaluated using pulsed wave Doppler and M-mode echocardiography in 60 hypertensive patients and 30 control subjects. The hypertensive group was divided into two subgroups on the basis of h/r value(mean+2SD of normal value observed in the control group). One subgroup consisted of 28 patients with normal h/r (<(0.4)) and the other consisted of 32 patients with increased h/r(>(0.4)). ResultsThe peak flow velocity (Peak E) and the deceleration half - time (DHT) of early mitral flow were significantly different between the two subgroups. In the hypertensive group, significant correlations were demonstrated between the RWT and the Peak E (r=(-0.742), P<(0.001)), DHT(r=(0.705), P<(0.001)). And poor correlations were found between the left ventricular mass (LVM) and the Peak E (r=(-0.425), P<(0.001)), DHT(r=(0.324), P<(0.001)). ConclusionThese data indicate that the influence of RWT upon the patterns of left ventricular filling is obvious in patients with hypertension.