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Pneumocystis pneumonia in HIV-positive adults, Malawi
Authors:van Oosterhout Joep J G  Laufer Miriam K  Perez M Arantza  Graham Stephen M  Chimbiya Nelson  Thesing Phillip C  Alvarez-Martinez Miriam J  Wilson Paul E  Chagomerana Maganizo  Zijlstra Eduard E  Taylor Terrie E  Plowe Christopher V  Meshnick Steven R
Affiliation:University of Malawi College of Medicine, Blantyre, Malawi.
Abstract:In a prospective study of 660 HIV-positive Malawian adults, we diagnosed Pneumocystis jirovecii pneumonia (PcP) using clinical features, induced sputum for immunofluorescent staining, real-time PCR, and posttreatment follow-up. PcP incidence was highest in patients with the lowest CD4 counts, but PcP is uncommon compared with incidences of pulmonary tuberculosis and bacterial pneumonia.
Keywords:Pneumocystis pneumonia   HIV   Malawi   PCR   incidence   diagnosis   dispatch
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