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鸦胆子油乳剂治疗恶性胸腔积液58例疗效观察
引用本文:宋小平,陈志强,田进涛,陈炎. 鸦胆子油乳剂治疗恶性胸腔积液58例疗效观察[J]. 陕西医学杂志, 2004, 33(11): 1003-1004
作者姓名:宋小平  陈志强  田进涛  陈炎
作者单位:清华大学第一附属医院胸外科,北京,100016
摘    要:目的 :观察鸦胆子油乳剂胸腔内注射治疗恶性胸腔积液的疗效和副作用。方法 :对 5 8例恶性胸腔积液患者 ,采用胸腔穿刺或放置引流管排尽胸水后 ,胸腔内每次注入鸦胆子油乳剂 5 0~ 1 0 0 ml,隔 3日 1次 ,最多 4次为 1疗程 ,1月后观察疗效和副作用。结果 :鸦胆子油乳剂治疗恶性胸腔积液的有效率为 96.5 % ( 5 6/5 8) ,不良反应为发热 ( <38℃ )和轻度胸痛各 1例。结论 :鸦胆子油乳剂腔内注射治疗恶性胸腔积液疗效显著 ,副作用轻 ,值得进一步推广使用。

关 键 词:胸腔积液  恶性/药物疗法  乳状剂/治疗应用  @鸦胆子油乳剂

The results of 58 cases with malignant pleural effusion treated with brucea javanica oil emulsion
Affiliation:Beijing 100016
Abstract:Objective: To evaluate the therapeutic and side effects of Brucea javanica oil emulsion (BJOE) in the treatment of malignant pleural effusion by thoracic injection . Methods: From April 1989 to March 2003, we have used BJOE to treate 58 cases of malignant pleural effusion . A dose of 50~100ml BJOE was injected intrapleurelly, once every 3 days, 4 times for a course of treatment, then the effects and side effects were observed after one month. Results: The effective rate was 96.5% (56/58). The side effects were fever(<38°C, 1 case) and slight thoracalgia (1 case). Conclusion: Brucea javanica oil emulsion has good curative effect and low side effect in the treatment of malignant pleural effusion .
Keywords:Pleural effusion  malignant/drug fherapy Emulsions/therapeutic use @Brucea javanica oil emulsion
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