| FK506和环孢素A对肾移植患者血脂影响的比较 |
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| 引用本文： | 侯小飞,马潞林,王国良,唐文豪,付燕. FK506和环孢素A对肾移植患者血脂影响的比较[J]. 临床泌尿外科杂志, 2005, 20(1): 17-19 |
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| 作者姓名： | 侯小飞 马潞林 王国良 唐文豪 付燕 |
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| 作者单位： | 北京大学第三医院泌尿外科,北京,100083;北京大学第三医院泌尿外科,北京,100083;北京大学第三医院泌尿外科,北京,100083;北京大学第三医院泌尿外科,北京,100083;北京大学第三医院泌尿外科,北京,100083 |
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| 摘 要： | 目的：比较FK506和环孢素A(CsA)对肾移植患者术后脂质代谢的影响。方法：将以FK506或CsA为主要免疫抑制剂的肾移植患者209例分成FK506组和CsA组，对两组术后3个月、6个月和1年的血脂变化进行比较。结果：CsA组治疗术后血脂增高的比例均明显高于FK506组，且CsA组患者的治疗前、后血脂水平亦有明显差异。结论：肾移植患者治疗应用FK506比CsA可能会有效地降低高脂血症的发生率。
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| 关 键 词： | 肾移植 高脂血症 FK506 环孢素A |
| 文章编号： | 1001-1420(2005)01-0017-03 |
| 修稿时间： | 2004-10-11 |
The effects comparison of FK506 and CsA on serum lipids in renal allograft recipients |
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| HOU Xiaofei MA LU lin WANG Guoliang TANG Wenhao FU Yan. The effects comparison of FK506 and CsA on serum lipids in renal allograft recipients[J]. Journal of Clinical Urology, 2005, 20(1): 17-19 |
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| Authors: | HOU Xiaofei MA LU lin WANG Guoliang TANG Wenhao FU Yan |
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| Affiliation: | HOU Xiaofei1 MA LU lin1 WANG Guoliang1 TANG Wenhao1 FU Yan1 |
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| Abstract: | Objective:Objectives: To compare the effects between tacrolimus (FK506) and cyclosporin(CsA) on serum lipids after renal transplantation.Methods:There were 209 renal recipients involved in this study, among which 116 on CsA treatment and 93 on tacrolimus treatment. Main follow-up time was three month, six month and one year after operation. Chi-square test was used during statistical analysis.Results:No significant difference of the serum lipids mean levels was found between two groups before operation. The percentage of patients with hyperlipidemia in CsA group was significantly higher than that in FK506 group in the three-month, six-month and one-year follow-up. Moreover, there are staring difference among various time in CsA group.Conclusions:FK506 may be superior to CsA with respect to its effect on serum lipids. |
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| Keywords: | Kidney transplantation Hyperlipidemia Tacrolimus Cyclosporin |
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