| 人参花蕾皂甙对失血性休克犬心、肝、肺组织SOD及五种金属元素含量的影响 |
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| 引用本文： | 邢德君,杜葵琴,孙连坤,张永和, 孙庆霞,丁家华,曹壮,孙乾.人参花蕾皂甙对失血性休克犬心、肝、肺组织SOD及五种金属元素含量的影响[J].中国病理生理杂志,1995(1). |
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| 作者姓名： | 邢德君 杜葵琴 孙连坤 张永和 孙庆霞 丁家华 曹壮 孙乾 |
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| 作者单位： | 长春白求恩医科大学病理生理教研室，吉林省临床检验中心长春职工医科大学 |
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| 摘 要： | 杂种犬１６只，按体重随机分为失血性休克（ｈｅｍｏｒｒｈａｇｉｃｓｈｏｃｋ，ＨＳ）组（８只），失血性休克（ＨＳ）人参花蕾皂甙（ｇｉｎｓｅｎｇｆｌｏｗｅｒｂｕｄｓａｐｏｎｉｎ）预治疗（ＨＳＧ）组（８只）。通过调整血容量使动脉血压维持于５．３～６．７ｋＰａ５ｈ，放血后５ｈ处死动物取心肌、肝、肺组织测微量元素铜（Ｃｕ）、锌（Ｚｎ）铁（Ｆｅ）及宏量元素钙（Ｃａ）、镁（Ｍｇ）及超氧化物歧化酶（ＳＯＤ）的含量。结果显示：ＨＳＧ与ＨＳ组比较肺组织Ｚｎ含量明显减少（Ｐ＜０．０１），心肌、肺和肝组织Ｃａ含量显著减少（Ｐ＜０．０５），而心肌、肺和肝组织ＳＯＤ含量明显增多（Ｐ＜０．００１，Ｐ＜０．００１，Ｐ＜０．０１）。作者对这些结果的意义进行了探讨。
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| 关 键 词： | 休克 人参 超氧化物歧化酶类 微量元素 |
Effect of ginseng flower bud saponin on SOD and five metal elements in dog tissues with hemorrhagic shock |
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| Xing De-Jun,Du Kui-Qin,et al.Effect of ginseng flower bud saponin on SOD and five metal elements in dog tissues with hemorrhagic shock[J].Chinese Journal of Pathophysiology,1995(1). |
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| Authors: | Xing De-Jun Du Kui-Qin |
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| Institution: | Xing De-Jun,Du Kui-Qin,et al Department of Pathophysiofogy Norman Bethune University of Medical Sciences,Changchun |
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| Abstract: | Sixteen hybrid dogs were divided into two groups: hemorrhagic shock gro- Up(HS ),and hemorrhagic shock pretreated with Abstractginseng flower bud saponin group(HSG). The arteral blood pressure were main tained at 5.3-6.7kPa by regulating the blood volu-me. Dogs were killed after 5h of shock. Myocardium,lung and liver were taken out foranalysis of Cu, Zn, Fe,Ca,Mg and superoxide dismutase(SOD).The result showed that znin lung of HSG group dogs was significantly lower than that of HS group(P<0.01),andCa in myocardim,lung and liver of dogs in HSG group were also lower(P<0 . 05). However, the SOD content in myocardium,lung and liver of dogs in HSG group were signi-ficantly higher than that of HS group(P<0. 001,P<0. 001,P<0.0l respectivly). |
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| Keywords: | H Shock Ginseng Superoxide dismutase Trace elements |
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