| 猪神经元胞体和轴突神经细丝组分的初步分析 |
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| 引用本文： | 钱振宇,周迎春,李一鸣,邓洁,王建枝. 猪神经元胞体和轴突神经细丝组分的初步分析[J]. 华中科技大学学报(医学版), 2000, 29(2) |
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| 作者姓名： | 钱振宇 周迎春 李一鸣 邓洁 王建枝 |
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| 作者单位： | 1. 同济医科大学九三级(七年制),武汉,430030
2. 同济医科大学基础医学院病理生理学教研室,武汉,430030 |
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| 摘 要： | 从猪神经元胞体和轴突中分离提取了神经细丝 (NF) ,对它们各自进行了电泳以分析其亚基构成并进行磷酸化程度定量分析 ,结果表明 NF分子由大中小三种亚基构成 ,胞体和轴突两种 NF的磷酸化程度存在显著性差异。这一方法将对阐明某些神经元退行性变疾病的机理提供有用的线索。
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| 关 键 词： | 神经细丝 亚基 磷酸化 |
Preliminary Analysis of Porcine Cytostic and Axonal Neurofilaments |
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| Qian Zhenyu,Zhou Yingchun,Li Yiming et al Seven Year Class of Grade ,Tongji Medical University,Wuhan. Preliminary Analysis of Porcine Cytostic and Axonal Neurofilaments[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 2000, 29(2) |
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| Authors: | Qian Zhenyu Zhou Yingchun Li Yiming et al Seven Year Class of Grade Tongji Medical University Wuhan |
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| Affiliation: | Qian Zhenyu,Zhou Yingchun,Li Yiming et al Seven Year Class of Grade 93,Tongji Medical University,Wuhan 430030 |
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| Abstract: | Both neurofilaments (NF) isolated from the porcine neural cell bodies and axons were subjected to the analysis on their constitutional subunits by using electrophoresis and the quantified phosphate content respectively. The result showed that NF consisted of three subunits with three different molecular weight. There was significant difference in phosphate contents between the two NF. The method may offer helpful clues to clarify some degeneration diseases of the neural system. |
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| Keywords: | neurofilament subunit phosphate content |
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