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Bacille Calmette-Guérin — associated neonatal hepatitis |
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| Authors: | B. Simma O. Dietze W. Vogel H. Ellemunter J. P. Guggenbichler |
| Affiliation: | (1) Department of Paediatrics, Innsbruck University Hospital, Anichstrasse 35, A-6020 Innsbruck, Austria;(2) Department of Pathology, Innsbruck University Hospital, Anichstrasse 35, A-6020 Innsbruck, Austria;(3) Department of Internal Medicine, Innsbruck University Hospital, Anichstrasse 35, A-6020 Innsbruck, Austria |
| Abstract: | We describe a full-term immunocompetent neonate who developed jaundice at 3 weeks of age. Physical examination disclosed no abnormalitics. Laboratory investigations showed direct reacting hyperbilirubinaemia and elevated liver enzymes. Liver biopsy revealed a noncaseating granulomatous hepatitis. The patient made an uneventful recovery within 4 weeks without therapy. Bacille Calmette-Guérin hypersensitivity reaction is suggested as the reason for this neonatal hepatitis. |
| Keywords: | BCG vaccination Granulomatous hepatitis Hypersensitivity reaction |
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