补中法、升阳法、补中升阳法对脾气虚模型补气健脾作用的研究

目的:观察补中法、升阳法、补中升阳法对脾气虚模型的补气健脾作用,研究风药与补气健脾药配伍的增效作用.方法:健康Wistar大鼠随机分组,即对照组、脾气虚证模型组、治疗组(包括补中组、升阳组、补中升阳组),观察各组模型的一般情况.测定其血清D-木糖吸收率、红细胞计数、血红蛋白、血清总蛋白、血清白蛋白的量,并观察其含量变化.结果:经补中方、补中升阳方治疗后一般情况与造模组相比有显著统计学意义(P<0.01);各组大鼠血清D-木糖吸收率检测值的变化:补中组、补中升阳组能使指标有明显改善,与模型组比较,差异有统计学意义(P<0.01),且补中升阳组的作用优于单纯的补中组(P<0.05);红细胞计数、血红蛋白、血浆总蛋白、血浆白蛋白含量均有不同程度的上升;补中组、补中升阳组能使指标有明显改善,与造模组比较差异有统计学意义(P<0.05).结论:①补中法、补中升阳法对脾气虚证大鼠的消化系统功能的减弱,以及血常规、血生化改变有一定的改善作用,其中一部分指标补中升阳法优于补中法,升阳法对此无明显作用.②风药与补气药配伍,具有一定的增效补气健脾的作用.

EFFECTS OF THERAPY FOR STRENGTHENING MIDDLE PART OF BODY CAVITY,THERAPY FOR ELEVATING YANG,AND THEIR COMBINATION ON SPLEEN-QI INSUFFICIENCY ANIMAL MODELS

Objective:To observe the Qi-invigorating and spleen-strengthening effects of therapy for strengthening middle part of boby cavity(TSM),therapy for elevating Yang(TEY),and TSM combined with TEY(TSM+TEY)on spleen-Qi insufficiency models,so as to study the synergistic action between wind case drugs and Qi-invigorating and spleen-strengthening drugs.Methods: 50 healthy male wistar rats were divided randomly into normal group,spleen-Qi insufficiency models group,TSM group,TEY group ,and TSM+TEY group.General con...