腺苷脱氨酶的临床价值及其应用进展

腺苷脱氨酶（ADA）在某些疾病的早期诊断、治疗以及发病机制的研究中越来越受到关注。血清ADA活性是反映肝损伤的敏感指标，浆膜腔积液中ADA的测定在良恶性鉴别诊断上有重要价值。脑脊液ADA检测还可作为中枢神经系统疾病诊断和鉴别诊断的重要指标。近年研究表明ADA在结核病、糖尿病、恶性血液疾病、自身免疫性疾病的诊断及预后中也有重要价值。

Clinic application value and progress of adenosine deaminase

The clinic application value of the adenosine deaminase （ADA） determination gets nlore and nlore attention in the early diagnosis ,treatnlent and the study of pathogenesis. Serunl ADA activity is sensitive index of the liver damage,the determination of ADA in serous cavity effusion is also important in the differential diagnosis of benign and malignant. The evaluation of ADA in eerebrospinal fluid is served as the significant marker used in diagnosis and differential diagnosis of the central nervous system disease, in recent years, studies have shown that ADA are also important marker in the diagnosis and prognosis of TB, diabetes mellitus, malignant blood disease, autoimmune disease.