Chemonucleolysis: the state of the art |
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Authors: | James W. Simmons Eugene J. Nordby Alexander G. Hadjipavlou |
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Affiliation: | Alamo Bone and Joint Clinic, San Antonio, Texas, USA. |
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Abstract: | This review presents the history of chemonucleolysis, the techniques, indications, contraindications, and complications. Presenting an historical overview and comparison of success rates with surgical discectomy may provide a fresh understanding of the controversy surrounding chemonucleolysis and establish its efficacy in relation to more invasive treatments. A review of the literature from 1973 through 1998 for chemonucleolysis, open discectomy, and microdiscectomy provided published success rates for these procedures, and a mean rate with standard deviation was determined. In the experience and opinion of the authors, chemonucleolysis remains a viable alternative for patients who have exhausted all conservative means of treatment. Proper patient selection leads to success rates comparable to open discectomy and microdiscectomy. |
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Keywords: | Chemonucleolysis Open discectomy Microdiscectomy Chymopapain |
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