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Aetiology of acute sporadic hepatitis in adults in Kenya
Authors:C Greenfield  P Karayiannis  B M Wankya  M V Shah  P Tukei  S Galpin  T P Jowett  H C Thomas
Affiliation:1. Department of Medicine, Royal Free Hospital School of Medicine, Rowland Hill Street, London;2. Nairobi, Kenya, and Department of Medicine, Royal Free Hospital School of Medicine, Rowland Hill Street, London;3. Kenyatta National Hospital, Virus Research Centre, Royal Free Hospital School of Medicine, Rowland Hill Street, London
Abstract:Markers for acute hepatitis A virus (HAV), hepatitis B virus (HBV), and hepatitis non-A, non-B (HNANB) infections were examined in the sera of 94 patients presenting with acute hepatitis in Kenya. Hepatitis B virus was responsible for 70% of cases, HNANB for 18%, and HAV for only 12%. The use of an IgM anti-HBc assay increased the rate of diagnosis of acute HBV infection, thereby reducing the proportion of cases designated as NANB.
Keywords:viral hepatitis  hepatitis A, B  non-A  non-B
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