| 溴氰菊酯对大鼠不同脑区5-羟色胺含量的影响 |
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| 引用本文： | 王淑洁,郑勤龙,耿太保,罗玉姝.溴氰菊酯对大鼠不同脑区5-羟色胺含量的影响[J].卫生研究,1988(5). |
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| 作者姓名： | 王淑洁 郑勤龙 耿太保 罗玉姝 |
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| 作者单位： | 中国预防医学科学院劳动卫生与职业病研究所，中国预防医学科学院劳动卫生与职业病研究所，中国预防医学科学院劳动卫生与职业病研究所，中国预防医学科学院劳动卫生与职业病研究所 |
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| 摘 要： | 本实验研究了溴氰菊酯中毒大鼠各脑区内5-HT及其代谢产物5-HIAA含量的变化。结果表明当给大鼠经口染毒70mg/kg溴氰菊酯时,苍白球和大脑皮层内5-HT和5-HIAA的含量均降低,下丘脑内仅5-HIAA含量降低而延脑和中缝核群内的5-HT和5-HIAA的含量没有出现变化。这个现象提示溴氰菊酯的作用部位可能在中枢神经。
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| 关 键 词： | 溴氰菊酯 5-羟色胺 5-羟吲哚乙酸 |
Effect of Deltamethrin on Serotonin In the Brain of Rats |
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| Wang Shu-jie,Zheng Qing-long,Geng Tai-bao and luo yu-shu.Effect of Deltamethrin on Serotonin In the Brain of Rats[J].Journal of Hygiene Research,1988(5). |
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| Authors: | Wang Shu-jie Zheng Qing-long Geng Tai-bao and luo yu-shu |
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| Abstract: | The aim of this study was to investigate the neurotoxic effects of acute deltaraethriii poisoning on monoamine neurotransmitter of the central nervous system. Rats receives 70mg/kg O. P. deltamethrin. The results shoved that the level of serotonin (5-HT) and its metabolite 5-HIAA were decreased in the pallidum and cerebral cortex. The level of 5-HIAA was decreased in the hypothalamus only,but variation of 5-HT and 5-HIAA were not occurred in the brain oblongata and be raphe nuclei. This suggests that the site of action of deltamethrin may at the central nervous system. |
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| Keywords: | deltamethrin serotonin 5-hydroxyindole-3-acetic acid |
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