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类风湿性关节炎患者关节炎支原体的感染状况
引用本文:陆亚华. 类风湿性关节炎患者关节炎支原体的感染状况[J]. 现代实用医学, 2003, 15(2): 78-79
作者姓名:陆亚华
作者单位:213003,江苏省常州市第一人民医院
摘    要:目的:了解类风湿性关节炎(RA)患者关节炎支原体(Mar)的感染状况。方法:用套式聚合酶链反应(nPCR)法对本院2001年1月—2002年9月72例RA患者的咽拭子、睑结膜拭子、尿道拭子以及血液和关节液标本中的Mar核酸进行检测,并测定阳性株的DNA序列。结果:在48例咽拭子、37例睑结膜拭子、19例尿道拭子以及48例血液标本和26例关节液标本中,各检出1例阳性株,阳性率分别为2.1%、2.7%、5.3%、2.1%和3.8%。上述5例Mar nPCR阳性株的DNA序列与国际典型株完全一致。结论:RA患者体内存在Mar感染。

关 键 词:类风湿性关节炎 关节炎 支原体 感染
文章编号:1671-0800(2003)02-0078-02
修稿时间:2002-12-09

Mycoplasma arthritis infection in patients with rheumatoid arthritis
LU Ya Hua. Changzhou No. Hospital,Changzhou ,Jiangsu China. Mycoplasma arthritis infection in patients with rheumatoid arthritis[J]. Modern Practical Medicine, 2003, 15(2): 78-79
Authors:LU Ya Hua. Changzhou No. Hospital  Changzhou   Jiangsu China
Affiliation:LU Ya Hua. Changzhou No.1 Hospital,Changzhou 213003,Jiangsu China
Abstract:Objective To understand the condition of mycoplasma arthritis (Mar) infection in patients with rheumatoid arthritis(RA). Methods The Mar in throat,eyelid,urethral swabs and serum,synovial fluid specimens of 72 patients with RA were detected by nested polymerase chain reaction (nPCR).DNA sequence of positive strains was examined.Results One strain of Mar was isolated from 48 throat,37 eyelid,19 urethral swabs and 48 serum,26synovial fluid specimens,respectively. DNA sequence of above 5 positive strains was quite same as model strain. Conclusion Mar infection may exists in the patients with RA.
Keywords:Arthritis  rheumatoid Myoplasma infecticon PCR
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