|
|||||
|
|
| CD44v6在胰腺癌组织中的表达及意义 | |
| 引用本文： | 王鹏,李航宇,刘忠,刘万涛,张静.CD44v6在胰腺癌组织中的表达及意义[J].中国医科大学学报,2003,32(5):437-438. |
| 作者姓名： | 王鹏 李航宇 刘忠 刘万涛 张静 |
| 作者单位： | 1. 中国医科大学附属第一医院肿瘤内科,辽宁,沈阳,110001 2. 中国医科大学附属第一医院普外科 3. 沈阳市第七人民医院外科 4. 本钢职工总医院急诊科 5. 沈阳市生殖医学技术中心 |
| 摘 要： | 目的 :探讨CD4 4v6表达与胰腺癌淋巴结转移、增殖活性的关系。方法 :应用免疫组化SP法检测 6 2例胰腺癌组织中CD4 4v6的表达。结果 :CD4 4v6的阳性率为 5 4 .84 % ;伴淋巴结转移者CD4 4v6的阳性率 (6 8.75 % ) ,明显高于无淋巴结转移者 (40 .0 0 % ) ,两组相比差异显著 (P <0 .0 5 ) ;CD4 4v6表达与胰腺癌增殖之间无一致性。结论 :CD4 4v6的表达与胰腺癌的浸润和转移密切相关 |
| 关 键 词： | CD44v6 胰腺癌 转移 |
| 文章编号： | 0258-4646(2003)05-0437-02 |
| 修稿时间： | 2002年9月4日 |
Expression of CD44 Variant Exon 6 in Pancreatic Cancer |
|
| WANG Peng ,LI Hang-yu ,LIU Zhong ,LIU Wan-tao ,ZHANG Jing.Expression of CD44 Variant Exon 6 in Pancreatic Cancer[J].Journal of China Medical University,2003,32(5):437-438. | |
| Authors: | WANG Peng LI Hang-yu LIU Zhong LIU Wan-tao ZHANG Jing |
| Institution: | WANG Peng 1,LI Hang-yu 2,LIU Zhong 3,LIU Wan-tao 4,ZHANG Jing 5 |
| Abstract: | Objective: Our aims were to evaluate the expression of CD44v6 in tissues of pancreatic cancer and to investigate its relationship with transformation and invasiveness of pancreatic cancer. Methods:The expression of CD44v6 was determined with SP immunohistochemical technique. Results:The positive rate of CD44v6 was 54.84%,while the positive rate in patients with lymph node metastasis was 68.75%, which was significantly higher than those without lymph node involvement(P<0.05). The proliferation of pancreatic cancer was not related to CD44v6. Conclusion:The expression of CD44v6 is closely related to metastasis and infiltration of pancreatic cancer. |
| Keywords: | CD44v6 pancreatic cancer metastasis |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |