Peripheral neuropathy as the presenting feature of multiple system atrophy |
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| Authors: | Carmelo Rodolico MD Antonio Toscano MD Giovanni De Luca MD Anna Mazzeo MD Rita Di Leo MD Sergio Baldari MD Paolo Girlanda MD Giuseppe Vita MD |
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| Institution: | (1) Institute of Neurologic and Neurosurgical Sciences, University of Messina, Via C. Valeria, 98125 Messina, Italy;(2) Neurologic Unit, Azienda Ospedaliera Papardo, Messina, Italy;(3) Department of Nuclear Medicine, University of Messina, Messina, Italy |
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| Abstract: | The authors report a case of multiple system atrophy (MSA) with an onset as a peripheral nerve involvement. Their patient,
a 55-year-old man, had a 3-year history of distal weakness and atrophy in upper limbs with dysesthesia in the feet. Other
identifiable causes of peripheral neuropathy were ruled out. The authors postulate that peripheral nervous system impairment
can anticipate the typical appearance of MSA, and they suggest that, in peripheral neuropathies with autonomic system dysfunction,
after excluding main causes of autonomic neuropathy, MSA may need to be suspected. |
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| Keywords: | peripheral neuropathy multiple system atrophy IBZM-SPECT |
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