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观察三维适形放射治疗结合同步化疗治疗Ⅲ期非小细胞肺癌的临床疗效
引用本文:史凌云,王伟,董海北,许猛军,吴小进.观察三维适形放射治疗结合同步化疗治疗Ⅲ期非小细胞肺癌的临床疗效[J].中国辐射卫生,2018,27(4):403-405.
作者姓名:史凌云  王伟  董海北  许猛军  吴小进
作者单位:徐州医科大学附属徐州市立医院肿瘤中心, 江苏 徐州 221200
摘    要:目的 研究三维适形放射治疗结合同步化疗在Ⅲ期非小细胞肺癌中的应用价值。方法 研究对象为我院2013年1月-2016年12月收治的Ⅲ期非小细胞肺癌患者,采用随机数字表法分成两组,对照组和实验组各80例。对照组予以同步化疗,实验组予以三维适形放射治疗联合同步化疗。分析和比较两组患者的治疗效果及生存率。结果 对照组的总有效率、生存率相比实验组要低,毒副作用发生率相比实验且要高,差别均有统计学意义(P<0.05)。结论 对Ⅲ期非小细胞肺癌患者应用三维适形放射联合同步化疗效果显著,能够有效提高患者的治疗效果以及生存质量。

关 键 词:三维适形放射治疗  同步化疗  III期非小细胞肺癌  临床疗效  
收稿时间:2018-02-20

Efficacy of chemotherapy combined with 3-dimensional conformal radiation therapy on advanced Ⅲ non-small cell lung cancer
SHI Lingyun,WANG Wei,DONG Haibei,XU Mengjun,WU Xiaojin.Efficacy of chemotherapy combined with 3-dimensional conformal radiation therapy on advanced Ⅲ non-small cell lung cancer[J].Chinese Journal of Radiological Health,2018,27(4):403-405.
Authors:SHI Lingyun  WANG Wei  DONG Haibei  XU Mengjun  WU Xiaojin
Institution:Xuzhou Municipal Hospital Affiliated to Xuzhou Medical University, Xuzhou 221200 China
Abstract:Objective To analyze the application value in stage Ⅲ non-small cell lung cancer by the combination of the 3d chemotherapeutic radiotherapy with synchronous chemotherapy. Methods The study of 160 cases of stage Ⅲ non-small-cell lung cancer in our hospital from January 2013 to December 2016. They were divided into two groups, and 80 patients were treated with synchronous chemotherapy. Eighty patients were given three dimensional chemotherapeutic radiotherapy combined with synchronous chemotherapy, set as the experimental group. To observe the progress of the patient's treatment and to analyze and compare the treatment outcomes and survival rates of two groups. Results The total efficiency of the patients in the experimental group was higher, and the difference in the data of the control group were statistically significant, which confirmed the statistical significance, (P<0.05). The survival rate of the patients in the experimental group was higher, and the difference between the experimental group and the control group was statistically significant, and (P<0.05). The incidence of adverse effects was low in the experimental group, and the difference between the experimental group and the control group was significant, and the significance of the evidence was statistically significant (P<0.05). Conclusion For patients with stage Ⅲ non-small cell lung cancer using three dimensional conformal radiotherapy in combination with synchronous chemotherapy, obvious effect, can effectively improve the therapeutic effect of patients as well as the quality of life.
Keywords:3 d Conformal Radiation  Synchronous Chemotherapy  Phase III Nonsmall-Cell Lung Cancer  Clinical Curative Effect  
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