青蛙皮及乳猪皮治疗深度烧伤创面的比较研究

目的探讨新鲜青蛙皮在治疗深Ⅱ度、Ⅲ度烧伤创面中的临床应用价值。方法将159例患者随机分为青蛙皮组和乳猪皮组，深Ⅱ度覆盖蛙皮35例，乳猪皮3l例。Ⅲ度创面换药及切痂植皮时覆盖蛙皮49例，乳猪皮44例。两组病人平均年龄、深Ⅱ度、Ⅲ度面积无显著差别。结果与乳猪皮比较，青蛙皮可减少深度创面愈合天数及抗生素使用天数，减少深度创面感染发生率，较少排异反应，增加细菌阴转率。结论青蛙皮用于烧伤创面具有较强的抗感染能力，较少排斥反应，是一种理想的烧伤创面生物敷料。

Effect of Frog and Suckling Pig Skin on Wound Healing in Deep Burn

Objective To evaluate the effect of live frog skin in the treatment of deep partial thickness and full thickness burn. Methods 159 burned patients were randomly divided into two groups: wounds treated with frog skin or suckling pig skin. Wounds were covered by frog skin(35 cases) or by suckling pig skin(31 cases) after surgical debridement or when the crust began to dissolve for patients with deep partial thickness burns, and by frog skin (49 cases) or by sucking pig skin(44 cases) after surgical debridment or autologous skin grafting and escharetomy for patients with full thickness burns. There was no significant difference between the two groups in mean age, burn area and burn type. Results Compared with the suckling pig skin, frog skin could remarkably decrease days of wound recovery and antibiotics administration, and reduced incidence of wound infections and rejection in patients with full thickness burns. Conclusions Frog skin possessed more powerful anti-infection ability, and rare rejection phenomenon in the treatment of burn wounds. It may be a suitable biological dressing for burn wounds.