妊娠期糖尿病孕妇的常见中医体质分布及糖脂代谢研究

目的:探讨妊娠期糖尿病(Gestational Diabetes Mellitus,GDM)孕妇的常见中医体质分布及糖脂代谢情况,为防治GDM提供理论依据.方法:随机选取265例GDM孕妇作为研究对象,采用体质调查问卷,判定GDM患者的中医体质类别.检测受试者的糖脂代谢指标[空腹血糖(Glucose,GLU)、餐后2 ...

A study on common TCM constitution types and glycolipid metabolism of pregnant women with gestational diabetes mellitus

Objective:Common TCM constitution types and glycolipid metabolism of pregnant women with GDM were evaluated.Methods:265 cases were randomly enrolled in this study.The TCM constitution types of patients were determined according to questionnaires.The glucolipid metabolism indexes(including GLU,2 h PG,HbA1c,TC,TG and LDL-C)were detected.The five common TCM constitution types were selected to compare the differences in glycolipid metabolism among all groups.Results:Five TCM constitution types were the Phlegm-dampness constitution(30.6%,81/265),dampness-heat constitution(23.8%,63/265),Qi deficiency constitution(16.2%,43/265),balanced constitution(10.2%,27/265)and Yang(阳)deficiency constitution(8.3%,22/265).In terms of glucolipid metabolism,TC and LDL-C levels in the Tanshi constitution group were higher than the Qixu constitution group and banlanced constitution group and Yangxu constitution group(P<0.05).There were no significant difference in GLU,2 h PG,HbA1c and TG levels among groups(P>0.05).Conclusion:The TCM constitution type of pregnant women with GDM is mainly biased constitution type,with Tanshi constitution accounting for the highest proportion.The difference in glucolipid metabolism is mainly reflected in lipid metabolism.Treatment should focus on eliminating dampness,removing phlegm and strengthening spleen,and pay attention to the regulation of lipid metabolism.