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Synthesis of New 6-[4-(2-Fluorophenylpiperazine-1-YL)]-3(2H)-Pyridazinone-2-Acethyl-2- (Substitutedbenzal)Hydrazone Derivatives and Evulation of Their Cytotoxic Effects in Liver and Colon Cancer Cell Lines
Authors:Özdemir  Zeynep  Başak-Türkmen  Neşe  Ayhan   İdris  Çiftçi  Osman  Uysal  Mehtap
Affiliation:1.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280, Malatya, Turkey
;2.Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Inonu University, 44280, Malatya, Turkey
;3.Department of Medical Pharmacology, Faculty of Medicine, Y?ld?r?m Beyaz?t University, 06100, Ankara, Turkey
;4.Department of Medical Pharmacology, Faculty of Medicine, Pamukkale University, 20160, Denizli, Turkey
;5.Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University, 06100, Ankara, Turkey
;
Abstract:Pharmaceutical Chemistry Journal - In this study, seven new 3(2H)-pyridazinone derivatives expected to show cytotoxic activity in liver and colon cancer cell lines were synthesized. Their...
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