蒽环类药物相关心脏毒性的研究进展 |
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引用本文: | 郭辅定,赖燕秋(综述),江洪(审校). 蒽环类药物相关心脏毒性的研究进展[J]. 疑难病杂志, 2021, 0(3): 299-303,309 |
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作者姓名: | 郭辅定 赖燕秋(综述) 江洪(审校) |
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作者单位: | 武汉大学人民医院心内科/武汉大学心脏自主神经研究中心/武汉大学心血管病研究所/心血管病湖北省重点实验室 |
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基金项目: | 国家自然科学基金资助项目(81770364、81530011)。 |
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摘 要: | 蒽环类药物是治疗恶性肿瘤最有效的化疗药物之一,临床广泛用于治疗血液系统恶性肿瘤和实体肿瘤.心脏毒性是蒽环类药物潜在的严重不良反应,也是限制其临床应用的重要考量因素.目前,蒽环类药物相关心脏毒性尚缺乏有效的治疗手段,早期监测和提前预防蒽环类药物相关心脏毒性的发生尤为重要.文章就蒽环类药物相关心血管疾病的发生机制、监测手段...
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关 键 词: | 蒽环类药物 心脏毒性 发病机制 不良反应 |
Research progress of anthracycline-related cardiotoxicity |
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Affiliation: | (Department of Cardiology, Renmin Hospital of Wuhan University,Hubei Province,Wuhan 430060,China) |
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Abstract: | Anthracyclines are one of the most effective chemotherapeutics for the treatment of malignant tumors,and are widely used clinically to treat hematological malignancies and solid tumors.Cardiotoxicity is a potentially serious adverse reaction of anthracyclines,and it is also an important factor limiting its clinical application.At present,there is no effective treatment for anthracycline-related cardiotoxicity.Early monitoring and prevention of anthracycline-related cardiotoxicity are particularly important.This article reviews the occurrence mechanism,monitoring methods and prevention and treatment strategies of anthracycline-related cardiovascular diseases,in order to provide new ideas for the clinical prevention and treatment of anthracycline-related cardiotoxicity. |
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Keywords: | Anthracyclines Cardiotoxicity Pathogenesis Adverse reaction |
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