血清尿酸、胆红素与冠心病关系的临床探讨

目的:探讨血尿酸、胆红素与冠心病发生、发展的关系。方法:随机抽取59例冠心病患者和52例健康者进行血尿酸、胆红素水平检测与对比分析。结果:冠心病组病人血尿酸水平明显升高(P<0.01),总胆红素、间接胆红素显著降低(P<0.05),且与冠脉病变程度相关;但直接胆红素水平无明显差异(P>0.05)。结论:血尿酸水平升高和胆红素水平降低与冠心病密切相关,早期干预有可能预防心血管事件的发生。

Clinical Discussion of the Relationship between the Levels of Serum Uric Acid,Bilirubin and Coronary Heart Disease

Objective: To investigate the relationship between the levels of serum uric acid,bilirubin and the occurrence of coronary heart disease(CHD).Methods: 59 cases of CHD patients and 52 cases of healthy controls were randomly chosen for observation and comparison of the levels of serum uric acid and bilirubin.Results: The levels of serum uric acid increased more significantly in CHD group than that in control group(P<0.01),but total and direct bilirubin concentrations reduced in CHD group more markedly than that in control group(P<0.05).These are related with the crown arteries pathological change degree.There was little difference in indirect bilirubin of two groups(P>0.05).Conclusion: The increase of serum uric acid concentrations and the reduce of bilirubin concentrations are related to CHD.It is possible to prevent the cardiovascular event by way of early intervention.