男性与女性强直性脊柱炎的对比研究

目的　比较并分析男性与女性强直性脊柱炎 (AS)患者的病情及预后。方法　 130例AS患者中 ,男性 10 9例 ,女性 2 1例 ,将两组患者的起病年龄、关节受累及关节强直等病情进行全面比较。结果　男性AS患者起病较女性为早 (平均起病年龄分别为 2 0 1岁和 2 4 6岁 ,P <0 0 1) ;男性患者颈椎及外周关节受累率 (分别为42 2 %和 5 6 9% )显著高于女性患者 (分别为 19 0 %和 2 8 6 % ,P均 <0 0 5 ) ;男性患者中 ,分别有 72 5 %和43 1%发展为腰椎强直和胸廓强直 ,而女性患者分别为 47 6 %和 9 5 % (P <0 0 5和P <0 0 1)。结论　女性AS与男性AS相比 ,其病情相对较轻 ,预后较好

Comparison between male and female ankylosing spondylitides

Objective To compare and analyze the clinical feature and prognosis of male and female ankylosing spondylitides (AS).Methods Of 130 AS patients,there were 109 male cases and 21 female cases.The clinical feature including age of onset,joint involvement,and joint ankylosis was compared between the two groups.Results The average age of onset of male AS was younger than that of female AS (20.1 years and 24.6 years,respectively,P<0.01).The prevalence of cervical spine and peripheral joint involvement if male patients (42.2% and 56.9%) was higher than that of female patients (19.0% and 28.6%,P both <0.05).Of the male patients,72.5% developed lumbar spine ankylosis and 43.1% developed chest ankylosis (of the female patients,47.6% and 9.5%,P<0.05 and P<0.01,respectively).Conclusion Compared with male AS,female AS had milder clinical symptoms and better prognosis.