| Abstract: | The character of changes in postsynaptic inhibition in spinal  -motoneurons of cats was studied in the course of experimental local botulinus poisoning. At the beginning of development of the local paralytic syndrome a marked decrease in the amplitude of the reciprocal, and a smaller decrease in amplitude of the polysynaptic IPSPs was observed. On the appearance of total paralysis of the muscles from botulinus poisoning the reciprocal and polysynaptic IPSPs were inhibited even more, but they never disappeared completely and were never converted into depolarization potentials. During the development of the IPSP the synaptic permeability of the motneurons as a rule was reduced.Department of Pathological Physiology, N. A. Semashko Moscow Medical Stomatological Institute. Department of Pathological Physiology, Saratov Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. D. Ado.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 6, pp. 651–654, June, 1977 |
