| 全身毛发受累的念珠形发1例 |
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| 引用本文： | 熊春萍,侯显曾,张滨岳,黄卓辉. 全身毛发受累的念珠形发1例[J]. 临床皮肤科杂志, 2002, 31(3): 181-183 |
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| 作者姓名： | 熊春萍 侯显曾 张滨岳 黄卓辉 |
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| 作者单位： | 广州医学院第一附属医院皮肤科,广州,510120 |
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| 摘 要： | 报告1例21岁男性患者，自幼头发稀少，头部营养不良性秃发，全身毛发程度不一的串珠状改变或黑点状断发，伴毛囊角化性丘疹。光镜见典型串珠状改变。扫描电镜观察胸毛，一根毛小皮消失，一根存在，狭窄部见明显的纵嵴，纵沟。病理见毛囊稀少、萎缩。
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| 关 键 词： | 全身性念珠形发 角蛋白基因 基因突变 毛发疾病 |
| 文章编号： | 1000-4963(2002)03-0181-03 |
| 修稿时间： | 2000-11-20 |
Generalized monilethrix: A case report |
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| XIONG Chun ping,HOU Xian zeng,ZHANG Bin yue,HUANG Zhuo hui. Generalized monilethrix: A case report[J]. Journal of Clinical Dermatology, 2002, 31(3): 181-183 |
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| Authors: | XIONG Chun ping HOU Xian zeng ZHANG Bin yue HUANG Zhuo hui |
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| Abstract: | A case of generalized monilethrix was reported. A 21 year old male patient presented dystrophic alopecia, variable beaded hair or black spotted broken hair with follicular keratosis all over the body. SEM of two chest hairs showed the absence of cuticle in one of the two examined . Longitudinal ridges and ditches were noted on the surface, especially on the narrow internodes. Histopathology of scalp showed sparse follicles, atrophic follicles without hair. |
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| Keywords: | monilethrix generalized keratin gene mutation |
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