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细胞外灌流对骨骼肌细胞介电谱的影响
引用本文:马青,王立洪,侯晓荣.细胞外灌流对骨骼肌细胞介电谱的影响[J].生物医学工程学杂志,2005,22(6):1112-1115.
作者姓名:马青  王立洪  侯晓荣
作者单位:1. 宁波大学,医学院,宁波,315211
2. 宁波大学,理学院,宁波,315211
基金项目:浙江省自然科学基金资助项目(M303044),浙江省教育厅资助项目(20030471)
摘    要:通过灌流的方法,探讨细胞外液对骨骼肌细胞介电谱的影响,应用非线性Co le-Co le公式的曲线拟合与数值计算,比较灌流后骨骼肌细胞介电谱参数,结果表明:(1)低频段介电常数Lε和高频段电导率hκ随着细胞外灌流液电导率的降低而减少;(2)细胞外灌流对骨骼肌细胞介电谱的特征频率(fC 1,fC 2)影响不大;(3)细胞外灌流主要影响骨骼肌细胞Δε″和tgδ的峰值。

关 键 词:灌流  骨骼肌  介电常数  电导率  介电谱
收稿时间:2003-09-25
修稿时间:2003-09-252004-03-12

The Effect of Extracellular Perfusion on Dielectric Spectroscopy of Skeletal Muscle Cells
Ma Qing,Wang Lihong,Hou Xiaorong.The Effect of Extracellular Perfusion on Dielectric Spectroscopy of Skeletal Muscle Cells[J].Journal of Biomedical Engineering,2005,22(6):1112-1115.
Authors:Ma Qing  Wang Lihong  Hou Xiaorong
Institution:1.Medical School, Ningbo University, Ningbo 315211,China; 2.Faculty of Science, Ningbo University, Ningbo 315211,China
Abstract:The dielectric spectroscopy of the skeletal muscle cells is approached by extracellular perfusion, using curve fitting and numerical calculation with nonlinear Cole-Cole equation, and the dielectric parameter of skeletal muscle cells is compared after perfusion, The results show: (1) the permittivy at low frequency (epsilon1) and the conductivity at hight frequency (kappa(h)) reduces in keeping with extracellular perfusate; (2) the effect of extracellular perfusion on the characteristic frequency (f(c1),f(c2)) is small; (3) the extracellular perfusion mostly influences the peaks of deltaepsilon" and tgdelta for the skeletal muscle cells.
Keywords:Perfusion Skeletal muscle Permittivity Conductivity Dielectric spectroscopy
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