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Isolated fibromuscular dysplasia of the coronary arteries with spontaneous dissection and myocardial infarction
Authors:J T Lie  K K Berg
Affiliation:1. Division of Plastic & Reconstructive Surgery, Virginia Commonwealth University, 830 East Main Street, Richmond, VA 23298, USA;2. Department of Plastic & Maxillofacial Surgery, University of Virginia, 1215 Lee Street, Charlottesville, VA 22903, USA;1. Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA;2. Department of Nephrology, The Affiliated Hospital of Xuzhou Medical College, Xuzhou, China;3. Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, USA;1. Department of Obstetrics and Gynecology, University of Turku and Turku University Hospital, Turku, Finland;2. Institute of Biomedicine, Department of Physiology, University of Oulu, Finland;3. The Research Centre of Applied and Preventive Cardiovascular Medicine (CAPC), University of Turku, Finland;4. Department of Pathology, Turku University Hospital, Finland;5. Department of Cell Biology and Anatomy, University of Turku, and Turku Center for Disease Modeling (TCDM), Finland;6. Department of Obstetrics and Gynecology, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland;7. Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland;1. Department of Respiratory Medicine, Iwakuni Clinical Center, Iwakuni, Japan;2. Department of General Internal Medicine 4, Kawasaki Medical School, Okayama, Japan;3. Department of Respiratory Medicine, Japanese Red Cross Okayama Hospital, Okayama, Japan;4. Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan;5. Department of Respiratory Medicine, Chugoku Central Hospital, Fukuyama, Japan;6. Department of Medical Oncology, Yamaguchi-Ube Medical Center, Ube, Japan;7. Department of Allergy and Respiratory Medicine, Okayama University Hospital, Okayama, Japan;8. Department of Thoracic Oncology and Medicine, Shikoku Cancer Center, Matsuyama, Japan;9. Department of Medical Oncology, Okayama Rosai Hospital, Okayama, Japan;10. Department of Respiratory Medicine, Fukuyama Medical Center, Fukuyama, Japan;11. Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan;1. Department of Rheumatology/Paediatric Rheumatology Unit, Hospital Universitario Severo Ochoa, Madrid, Spain;2. Department of Pediatric Hematology/Oncology and Blood & Marrow Transplant, Cleveland Clinic, OH, USA;3. Pathologic Anatomy Department, Hospital Universitario Severo Ochoa, Madrid, Spain;4. Center for Pediatric Rheumatology and Immunology Cleveland Clinic, OH, USA;1. Department of Oncology, Mount Vernon Cancer Centre, Northwood HA6 2RN, UK;2. Department of Histopathology, East and North Hertfordshire NHS Trust, Coreys Mill Lane, Stevenage, Hertfordshire SG1 4AB, UK;3. Princess Alexandra Hospital, Hamstel Road, Harlow, Essex CM20 1QX, UK
Abstract:Fibromuscular dysplasia (FMD) is a segmental, nonatherosclerotic vascular disease of unknown etiology. Both the renal and extrarenal arterial FMD may have focally deficient or absent muscular media, and spontaneous dissection is a serious complication of this arterial wall abnormality. Although FMD may be found in virtually any small and medium-sized arteries, to our knowledge, FMD of the coronary arteries previously has not been documented convincingly in the literature. This article describes one such unusual occurrence of FMD in the coronary arteries with spontaneous dissection and myocardial infarction.
Keywords:
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