| 荧光定量PCR法检测母乳巨细胞病毒感染和母婴传播 |
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| 引用本文： | 陈倩,钟天鹰,张其华.荧光定量PCR法检测母乳巨细胞病毒感染和母婴传播[J].中国优生与遗传杂志,2005,13(11):42-43. |
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| 作者姓名： | 陈倩 钟天鹰 张其华 |
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| 作者单位： | 南京医科大学附属南京市儿童医院儿科研究所,210008 |
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| 摘 要： | 目的了解母乳人巨细胞病毒（HCMV）感染状况和母婴传播情况.方法应用荧光定量PCR（FQ-PCR）法检测390份母乳中HCMV-DNA含量,其中236份母乳配对与患儿血液或尿液中HCMV-DNA含量作一定分析.结果可疑或确诊HCMV感染患儿母亲母乳HCMV-DNA阳性率达71.28%,HCMV-DNA阳性母乳喂养的婴儿,其血或尿HCMV-DNA阳性率明显高于HCMV-DNA阴性母乳喂养的婴儿.结论HCMV感染母乳是婴儿获得性感染的主要途径.
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| 关 键 词： | 人巨细胞病毒 母乳 荧光定量PCR法 |
| 文章编号： | 1006-9534（2005）11-0042-02 |
| 收稿时间： | 2004-11-25 |
| 修稿时间： | 2004年11月25 |
Investigation on situation and transmission of breast milk with HCMV infection |
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| CHEN Qian,ZHONG Tian-ying,ZHANG Qi-hua.Investigation on situation and transmission of breast milk with HCMV infection[J].Chinese Journal of Birth Health & Heredity,2005,13(11):42-43. |
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| Authors: | CHEN Qian ZHONG Tian-ying ZHANG Qi-hua |
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| Abstract: | Objective:To investigate the situation and transmission of breast milk with HCMV infection. Methods: FQ-PCR method was used to detect HCMV - DNA in 390 speciments of breast milk and 236 paired spciments of blood or urine. Results: The positive rate of HCMV - DNA of breast milk was 71.28% ,The positive rate of HCMV - DNA of infants with the positive breast feeding was obviously higher than greast milk without HCMV - DNA. Conclution: Breast milk is important in transmission of HCMV infection. |
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| Keywords: | Human cytomegalovirus Breast milk: Fluorogenic quantitative PCR |
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